What are the interventions for patellofemoral (kneecap) pain?

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Last updated: March 19, 2025View editorial policy

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From the Guidelines

For patients with patellofemoral pain, delivering knee-targeted exercise therapy, with supportive interventions as required, is the most effective approach, as it addresses the underlying causes of the pain and improves functional outcomes, as evidenced by the most recent and highest quality study 1.

Key Interventions

  • Deliver knee-targeted exercise therapy, with a focus on hip and knee strengthening, as this has been shown to improve patellofemoral pain outcomes 1
  • Education should underpin all interventions, adjusted to reflect the needs of the person, to challenge inaccurate beliefs, build confidence, and promote autonomy 1
  • Consider supportive approaches, such as prefabricated foot orthoses, movement/running retraining, and taping, based on subjective and objective findings 1

Exercise Therapy

  • Prescribe exercise therapy relative to specific severity and irritability, with a greater focus on hip exercises in people with poor tolerance to loaded knee flexion 1
  • Modify task/load/intensity/frequency as required to ensure effective and safe exercise therapy 1

Additional Considerations

  • Objectively evaluate physical impairments, including muscle strength, movement patterns, and tissue tolerance to load, to inform treatment selection 1
  • Consider the contextual factors related to symptoms, such as fear avoidance during functional tasks, to develop an effective treatment plan 1 By prioritizing knee-targeted exercise therapy, education, and supportive interventions, healthcare providers can effectively manage patellofemoral pain and improve patient outcomes, as supported by the most recent and highest quality evidence 1.

From the Research

Interventions for Patellofemoral Pain

The following interventions are used to treat patellofemoral pain:

  • Exercise therapy to strengthen the quadriceps, as studied in 2 and 3
  • Physiotherapy interventions, including specific vastus medialis obliquus or general quadriceps strengthening and/or realignment procedures (tape, brace, stretching), as mentioned in 3
  • Hip, knee, and core strengthening as well as stretching and aerobic exercise, as discussed in 4
  • Patellofemoral and tibiofemoral joint mobilizations, patellofemoral taping, neuromuscular training, and gait retraining, as mentioned in 4
  • Correction of imbalance between vastus medialis and vastus lateralis, as discussed in 5
  • Improvement of postural control and coordination of the lower extremity, increase of quadriceps strength and when needed hip muscle strength, and restoration of good knee function, as mentioned in 5

Types of Exercise Therapy

Different types of exercise therapy have been studied, including:

  • Closed kinetic chain exercise (foot in contact with a surface), as compared to open kinetic chain exercise (foot not in contact with a surface) in 2
  • Quadriceps strengthening exercises, as studied in 2 and 3
  • Hip and core strengthening exercises, as discussed in 4

Other Interventions

Other interventions that have been studied include:

  • Intra-articular injections, as mentioned in 6
  • Neurotomy and neuromodulation techniques, as discussed in 6
  • Transcatheter intra-arterial therapies, as mentioned in 6
  • Corrective foot orthosis and progressive resistance brace, as studied in 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Exercise therapy for patellofemoral pain syndrome.

The Cochrane database of systematic reviews, 2003

Research

A systematic review of physical interventions for patellofemoral pain syndrome.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2001

Research

Anterior knee pain: an update of physical therapy.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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