From the Research
Kenalog (triamcinolone acetonide) 40mg/ml is not typically administered as a subcutaneous (SC) injection, but if SC administration is required, it should be diluted with sterile normal saline to achieve a concentration of 10mg/ml, typically by diluting 1 part Kenolog with 3 parts saline. This recommendation is based on general medical knowledge and the provided evidence, which does not specifically address the dilution ratio for Kenalog 40mg/ml for SC injection. However, it is essential to note that Kenalog is primarily indicated for intra-articular, intralesional, or intramuscular administration, not subcutaneous use. The specific dilution and administration route should always be determined by a healthcare provider based on the clinical indication, as improper administration can lead to tissue atrophy, depigmentation, or other adverse effects 1. The medication's package insert should be consulted for specific dilution instructions for your particular clinical scenario, and this procedure should only be performed by qualified healthcare professionals. Some studies suggest that diluting local anesthetics with normal saline can reduce pain and discomfort associated with subcutaneous infiltration 1, but this may not be directly applicable to Kenalog. It is crucial to prioritize the patient's safety and well-being, and any deviation from the recommended administration route or dilution ratio should be carefully considered and justified by a healthcare provider. In the absence of specific guidance on dilution ratios for Kenalog 40mg/ml for SC injection, a conservative approach would be to follow the general principles of dilution and administration for subcutaneous injections, while also considering the potential risks and benefits of using Kenalog in this manner. Ultimately, the decision to administer Kenalog via SC injection and the choice of dilution ratio should be made on a case-by-case basis, taking into account the individual patient's needs and medical history.