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Differential Diagnosis for a Lump/Mass in the Arm Pit

Single Most Likely Diagnosis

  • Lipoma: A benign tumor composed of fat tissue, which is common in the axillary region and can grow in size over time.
  • Cyst: Such as an epidermoid cyst or sebaceous cyst, which can occur in the axilla and may increase in size.

Other Likely Diagnoses

  • Lymphadenopathy: Enlargement of lymph nodes in the axilla, which can be due to infection, inflammation, or other benign conditions.
  • Abscess: A collection of pus in the axilla, often caused by bacterial infection, which can present as a growing lump.
  • Folliculitis or Furuncle: Inflammation of the hair follicles or a boil, which can occur in the axilla and may appear as a growing mass.
  • Hidradenitis Suppurativa: A chronic skin condition characterized by recurrent abscesses and nodules in the apocrine-gland-bearing areas, such as the axilla.

Do Not Miss Diagnoses

  • Breast Cancer: Although less common, breast cancer can metastasize to the axillary lymph nodes, presenting as a lump in the arm pit.
  • Lymphoma: A type of cancer that affects the immune system and can cause lymphadenopathy in the axilla.
  • Soft Tissue Sarcoma: A rare type of cancer that can occur in the axilla, presenting as a growing mass.

Rare Diagnoses

  • Tuberculosis: A bacterial infection that can cause lymphadenopathy in the axilla, although this is relatively rare in many parts of the world.
  • Cat-Scratch Disease: An infection caused by Bartonella henselae, which can lead to lymphadenopathy, including in the axilla.
  • Actinomycosis: A rare bacterial infection that can cause abscesses or masses in the axilla.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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