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Last updated: September 28, 2025View editorial policy

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Differential Diagnosis for Right Rib Pain

  • Single most likely diagnosis
    • Musculoskeletal strain: This is often the most common cause of rib pain, resulting from overuse, trauma, or poor posture. The pain is typically sharp and worsens with movement or deep breathing.
  • Other Likely diagnoses
    • Costochondritis: Inflammation of the cartilage that connects the ribs to the breastbone, often causing sharp pains in the chest wall.
    • Precordial catch syndrome: A condition characterized by sudden, sharp pains in the chest, often related to the muscles between the ribs.
    • Rib fracture: A break in one of the ribs, usually caused by trauma, which can be very painful.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pulmonary embolism: A blood clot in the lungs that can cause sudden, severe chest pain, often accompanied by shortness of breath.
    • Pneumonia: An infection in the lungs that can cause chest pain, fever, and difficulty breathing.
    • Myocardial infarction (heart attack): Although more commonly associated with left-sided chest pain, a heart attack can occasionally present with right-sided chest pain.
    • Spontaneous pneumothorax: A sudden collapse of the lung, which can cause severe chest pain and shortness of breath.
  • Rare diagnoses
    • Tietze's syndrome: A rare condition characterized by inflammation of the cartilage that connects the ribs to the breastbone, similar to costochondritis but often more severe.
    • Sickle cell crisis: A condition that occurs in people with sickle cell disease, where abnormal red blood cells can cause episodes of severe pain, including chest pain.
    • Osteomyelitis of the rib: A rare infection of the bone that can cause pain, fever, and swelling in the affected area.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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