Treatment for General Spider Bites with No Systemic Reaction
For general spider bites with no systemic reaction, treatment should include cleaning the wound with soap and water, applying cold compresses, and using oral antihistamines for pain and itching; antibiotics are not necessary unless there is evidence of secondary infection. 1, 2
Initial Management
Wound Cleaning and Assessment
Symptomatic Relief
Important Considerations
What NOT to Do
- Avoid inappropriate treatments such as:
Special Situations
Fire Ant Stings: These typically cause a sterile pseudopustule within 24 hours. The vesicle should be left intact and kept clean to prevent secondary infection 1
Potential for Infection: If signs of infection develop (increasing redness, warmth, purulent drainage), wound cultures should be obtained to guide antibiotic therapy 2, 3
- Be aware that some spider bite infections have been found to contain methicillin-resistant Staphylococcus aureus (MRSA), which may require specific antibiotic coverage 3
Tetanus Prophylaxis: Ensure tetanus immunization is current 2
When to Seek Medical Attention
- If the bite area develops increasing pain, redness, or swelling beyond 2-3 days
- If a necrotic lesion develops (may indicate a brown recluse spider bite) 4, 5
- If any systemic symptoms develop (muscle cramping, severe pain, hypertension, diaphoresis) which could indicate a black widow spider bite 4, 6
- For bites on the face, due to cosmetic concerns and proximity to vital structures 2
Monitoring
- Most local reactions are self-limited and resolve within a few days
- Patients who have had large local reactions to insect stings may be at up to 10% risk of eventually having a systemic reaction to subsequent stings 1
- Monitor for signs of secondary infection, which would require antibiotic therapy
By following these guidelines, most uncomplicated spider bites can be managed effectively with minimal risk of complications or progression to more serious conditions.