Vitamin D 50,000 Units with Birth Control Pills and TRELEGY
Yes, you can safely take vitamin D 50,000 units while on birth control pills and TRELEGY (fluticasone furoate, umeclidinium, and vilanterol) as there are no significant drug interactions between these medications.
Safety of High-Dose Vitamin D
High-dose vitamin D supplementation at 50,000 IU is commonly used for treatment of vitamin D deficiency and is generally safe when used appropriately:
- Vitamin D 50,000 IU weekly or twice weekly is an established therapeutic regimen for treating vitamin D deficiency 1
- Studies have shown that doses of 50,000-100,000 IU/week of vitamin D3 for up to 12 months were safe and effective without causing toxicity 2
- No significant safety concerns have been reported with high-dose vitamin D supplementation when used for appropriate indications 3
Considerations with Birth Control Pills
There are no known clinically significant interactions between vitamin D supplements and oral contraceptives:
- No guidelines or drug labels indicate contraindications between vitamin D and birth control pills
- Oral contraceptives do not significantly alter vitamin D metabolism in a way that would require dose adjustment
- Birth control pills do not increase risk of vitamin D toxicity
Considerations with TRELEGY
TRELEGY contains three medications (fluticasone furoate, umeclidinium, and vilanterol):
- Fluticasone is a corticosteroid that may affect calcium metabolism, but there are no direct contraindications with vitamin D supplementation
- Umeclidinium and vilanterol (bronchodilators) have no known interactions with vitamin D
- No specific warnings exist regarding combining TRELEGY with vitamin D supplements
Important Precautions
While the combination is generally safe, be aware of these precautions:
- High-dose vitamin D (50,000 IU) should only be taken under medical supervision and for specific indications such as documented vitamin D deficiency
- Typical dosing for vitamin D deficiency is 50,000 IU weekly for 8 weeks, followed by maintenance therapy of 1,500-2,000 IU daily 4
- Prolonged use of high-dose vitamin D without monitoring can potentially lead to hypercalcemia and kidney issues 5
- Regular monitoring of vitamin D levels, serum calcium, and kidney function is recommended when taking high-dose vitamin D
Appropriate Vitamin D Dosing
The appropriate vitamin D dose depends on your specific situation:
- For general maintenance in vitamin D sufficient individuals: 1,000-2,000 IU daily
- For vitamin D deficiency: 50,000 IU weekly for 8 weeks, then maintenance therapy 4
- For severe malabsorption cases: 50,000 IU 1-3 times weekly may be needed 4
Conclusion
While vitamin D 50,000 units can be safely taken with birth control pills and TRELEGY, this high dose should only be used under medical supervision for specific indications like vitamin D deficiency. Ensure your healthcare provider is aware of all medications you're taking and is monitoring your vitamin D levels appropriately.