Differential Diagnosis for Peeling Hands in an 8-Year-Old Female
- Single Most Likely Diagnosis
- Kawasaki Disease: Although more commonly associated with fever, rash, and lymphadenopathy, Kawasaki disease can cause peeling of the skin on the hands and feet during its subacute phase. It's a leading cause of acquired heart disease in children, making it a critical consideration.
- Other Likely Diagnoses
- Eczema (Atopic Dermatitis): Can cause dryness and peeling of the skin, especially if not properly managed. It's common in children and can be exacerbated by environmental factors.
- Psoriasis: Although less common in children, psoriasis can cause skin peeling. It often presents with well-demarcated, erythematous plaques.
- Contact Dermatitis: An allergic reaction or irritation from substances like soap, detergent, or certain plants can lead to peeling skin on the hands.
- Do Not Miss Diagnoses
- Staphylococcal Scalded Skin Syndrome (SSSS): A serious condition caused by staphylococcal toxins that can lead to widespread skin peeling. It's life-threatening and requires immediate medical attention.
- Toxic Epidermal Necrolysis (TEN): A severe skin condition usually triggered by medications, leading to skin peeling and detachment. It's a medical emergency.
- Autoimmune Disorders (e.g., Pemphigus): Rare in children, but conditions like pemphigus can cause blistering and peeling of the skin.
- Rare Diagnoses
- Netherton Syndrome: A rare genetic disorder characterized by ichthyosiform dermatitis, hair shaft abnormalities, and an increased susceptibility to atopic diseases.
- Keratolytic Winter Erythema: A rare condition causing peeling of the skin on the palms and soles, often associated with cold weather.
- Peeling Skin Syndrome: A group of rare genetic disorders characterized by continuous shedding of the outer layer of the skin.