What is the clinical evidence for Eurycoma longifolia (Tongkat Ali) in humans and what is the recommended dosage?

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Last updated: March 19, 2025View editorial policy

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From the Research

Tongkat Ali (Eurycoma longifolia) has moderate evidence in humans for improving testosterone levels, sexual function, and reducing stress, with a recommended dosage of 200-400mg daily of a standardized extract. The clinical evidence for Eurycoma longifolia (Tongkat Ali) in humans is based on several studies, including a pilot study published in 2014 1, which investigated the effects of Tongkat Ali on physically active male and female seniors. The study found that treatment with 400mg of Tongkat Ali extract daily for 5 weeks resulted in significant increases in total and free testosterone concentrations and muscular force in men and women.

  • The study's findings suggest that Tongkat Ali may be beneficial for improving testosterone levels and sexual function in humans.
  • Another study published in 2016 2 reviewed the traditional uses, chemistry, and pharmacology of Eurycoma longifolia, and found that it has been used for centuries to treat various health conditions, including sexual dysfunction and aging.
  • A systematic review published in 2013 3 consolidated the safety and efficacy data available in the scientific literature on Tongkat Ali, and found that it has moderate evidence for improving testosterone levels, sexual function, and reducing stress.
  • However, it is essential to note that the evidence is not entirely consistent, and more research is needed to fully understand the effects of Tongkat Ali on human health.
  • The recommended dosage of Tongkat Ali is typically 200-400mg daily of a standardized extract, containing 2-3% eurycomanone or 22% eurypeptides, taken for at least 4-12 weeks for noticeable effects.
  • It is also important to choose products standardized to active compounds from reputable manufacturers, as quality can significantly impact the efficacy and safety of Tongkat Ali supplements.
  • Additionally, individuals with hormone-sensitive conditions, pregnant or nursing women, and people on medications should consult healthcare providers before using Tongkat Ali supplements.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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