From the Research
Tongkat Ali supplements pose significant risks to users, particularly those with hormone-sensitive conditions, heart conditions, liver or kidney disease, and should be approached with caution due to potential interactions with medications and variable quality and potency between products. The most common side effects of Tongkat Ali supplements include insomnia, restlessness, anxiety, and increased aggression due to its testosterone-boosting properties, as reported in various studies 1, 2, 3. Some users may experience digestive issues like nausea, upset stomach, or diarrhea. Tongkat Ali can also potentially interact with medications, particularly those that affect hormone levels, blood pressure medications, immunosuppressants, and blood thinners.
Key Considerations
- People with hormone-sensitive conditions such as prostate cancer, breast cancer, or endometriosis should avoid this supplement as it may worsen these conditions 2, 4.
- Those with heart conditions, liver or kidney disease should exercise caution when considering Tongkat Ali supplements 2, 3.
- The typical dosage ranges from 200-400mg daily of a standardized extract, but quality and potency vary widely between products 1, 2.
- Since Tongkat Ali supplements aren't strictly regulated by the FDA, there's a risk of contamination or mislabeling, emphasizing the need to purchase from reputable manufacturers and consult with a healthcare provider before starting this supplement, especially if you have underlying health conditions or take medications 4.
Recent Findings
A recent study published in 2024 found that Tongkat Ali supplementation enhances sleep and wake consolidation in wild-type mice, but its efficacy is limited in narcoleptic mice 5. This suggests that Tongkat Ali may have benefits for sleep quality, but more research is needed to understand its effects in humans. Another study from 2013 reported that Tongkat Ali supplementation improves stress hormone profile and certain mood state parameters, indicating its potential as an approach to mitigating the effects of chronic stress 3.
Recommendations
Given the potential risks and variable quality of Tongkat Ali supplements, it is crucial for individuals to consult with a healthcare provider before starting this supplement, especially if they have underlying health conditions or take medications. This consultation can help mitigate potential risks and ensure that the benefits of Tongkat Ali supplementation are maximized while minimizing its adverse effects.