How do you differentiate between complete heart block and Wenckebach's (Mobitz type I second-degree atrioventricular (AV) block) on an electrocardiogram (ECG)?

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Differentiating Complete Heart Block from Wenckebach on ECG

The key ECG difference between complete heart block and Wenckebach (Mobitz type I second-degree AV block) is that in complete heart block there is no conduction between atria and ventricles with complete AV dissociation, while in Wenckebach there is progressive PR prolongation before a dropped beat followed by a reset shorter PR interval.

Key Diagnostic Features

Complete Heart Block (Third-Degree AV Block)

  • Complete dissociation between P waves and QRS complexes
  • Regular P waves at normal sinus rate
  • Regular QRS complexes at a slower escape rhythm (junctional or ventricular)
  • No relationship between P waves and QRS complexes
  • QRS morphology:
    • Narrow QRS (≤120 ms): Block likely in AV node or within His bundle
    • Wide QRS (>120 ms): Block likely below the His bundle 1

Wenckebach (Mobitz Type I Second-Degree AV Block)

  • Progressive lengthening of PR intervals before a dropped beat (non-conducted P wave)
  • First PR interval after the dropped beat is shorter than the last conducted PR interval
  • Group beating pattern due to periodically dropped QRS complexes
  • Usually narrow QRS complexes (block typically at AV node level)
  • Often associated with a slowing sinus rate 1

Clinical Significance and Prognosis

Complete Heart Block

  • Usually associated with either junctional or ventricular escape mechanism
  • May be paroxysmal or persistent
  • Often symptomatic (syncope, presyncope)
  • Poor prognosis if untreated, especially if block is below His bundle
  • Usually requires permanent pacing 1

Wenckebach

  • Often asymptomatic, especially when occurring at rest
  • Usually represents block at the AV node level
  • Better prognosis than complete heart block
  • Often seen in healthy, active patients
  • May cause symptoms if frequent or occurring during exercise
  • Usually more responsive to autonomic manipulation (atropine, isoproterenol) 1

Common Pitfalls in Differentiation

  1. 2:1 AV Block Confusion: Cannot be classified as Mobitz I or II based on ECG pattern alone, as progressive PR prolongation cannot be observed with only one conducted beat 2

  2. Pseudo-AV Block: Concealed His bundle or ventricular extrasystoles may mimic both Wenckebach and complete heart block 2

  3. Isorhythmic Dissociation: When atrial and ventricular rates are similar, it may mimic AV block 1

  4. Atrial Bigeminy: Repetitive premature atrial contractions may be mistaken for AV block 1

  5. Wide QRS in Wenckebach: While typically associated with narrow QRS, Wenckebach can occasionally present with bundle branch block, making it harder to differentiate from complete heart block 1

Special Considerations

  • In complete heart block with atrial fibrillation, the ventricular response is slow (<50 bpm) and regular 1

  • Careful assessment of the relationship between P waves and QRS complexes is essential, particularly when the rates are similar 1

  • Mobitz type I (Wenckebach) block is almost always at the level of the AV node, while complete heart block can occur at various levels of the conduction system 1

  • Progression from Wenckebach to complete heart block is possible, especially in patients with underlying heart disease 3

By systematically analyzing the PR intervals, QRS morphology, and the relationship between P waves and QRS complexes, clinicians can accurately differentiate between these two important forms of heart block, which is crucial for appropriate management and prognostication.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Third-Degree Heart Block in Thalassemia major: A Case Report.

Iranian journal of pediatrics, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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