Negative Pressure Wound Therapy is the Best Dressing for Surgical Wounds After Necrotizing Fasciitis
Negative pressure wound therapy (NPWT) should be considered the best dressing option for surgical wounds after complete removal of necrosis in necrotizing fasciitis. 1
Rationale for NPWT in Post-Necrotizing Fasciitis Wounds
After aggressive surgical debridement of necrotizing fasciitis, wound management becomes challenging due to extensive tissue loss. NPWT offers several physiological benefits:
- Increases blood supply and tissue perfusion
- Reduces edema
- Absorbs wound fluids and exudates
- Helps inhibit infection
- Promotes and accelerates granulation tissue formation
- Removes bacterial contamination
- Facilitates wound closure 1
Application Timing and Considerations
NPWT should only be applied after:
- Complete removal of all necrotic tissue
- Control of the infection
- Adequate surgical debridement with no remaining necrosis 1
Special Considerations for Perineal Wounds
For necrotizing fasciitis involving the perineal area (Fournier's gangrene):
- NPWT can be combined with fecal diversion tubes to isolate the wound from fecal contamination
- This approach provides an effective alternative to colostomy while maintaining the benefits of negative pressure therapy 1
Alternative Dressing Options
While NPWT is recommended, other dressing options may be considered in specific situations:
Hydrofiber Dressings with Silver
Aquacel Ag® (hydrofiber dressing with ionic silver) can be an alternative when:
- NPWT is not available
- The wound is smaller or less complex
- Patient is not a candidate for NPWT
Benefits include:
- Forms a gel on contact with wound fluid
- Provides broad-spectrum antimicrobial properties
- Reduces local pain during dressing changes
- Maintains favorable wound moisture 2
Comprehensive Wound Management Approach
Initial Management
- Early and aggressive surgical debridement of all necrotic tissue
- Cultures of infected fluid and tissues during initial debridement
- Tailored antibiotic therapy based on culture results
- Repeated debridements until all necrotic tissue is removed 3
Subsequent Wound Care
- Apply NPWT after complete removal of necrosis
- Continue appropriate antibiotic therapy
- Provide nutritional support and glycemic control
- Consider reconstruction with skin grafts after adequate granulation tissue formation 1, 3
Monitoring and Follow-up
Monitor for:
- Signs of recurrent infection
- Adequacy of debridement
- Granulation tissue formation
- Need for additional surgical interventions
Pitfalls and Caveats
Delayed recognition: Early diagnosis and prompt surgical debridement are essential for survival. Mortality increases significantly when surgical debridement is delayed more than 24 hours after admission 4
Incomplete debridement: Ensure thorough removal of all necrotic tissue before applying NPWT or any other dressing 1, 3
Inappropriate antibiotic coverage: Use broad-spectrum antibiotics initially, then adjust based on culture results 3
Overlooking underlying conditions: Address predisposing factors such as diabetes mellitus, which is associated with higher risk for amputation 5
Underestimating the need for multiple debridements: On average, patients require multiple surgical interventions (mean of 7 in one study) 5
While NPWT has shown promising results in many wound types, it's important to note that the clinical evidence for its superiority over conventional wound dressing techniques specifically for necrotizing soft tissue infections is not definitively proven in randomized controlled trials 1. However, based on physiological benefits and clinical experience, it remains the recommended approach after complete debridement of necrotizing fasciitis.