Chymoral Forte Tablet Dosing
The recommended dosing for Chymoral Forte (alpha-chymotrypsin) tablets is 6 drops orally 4 times a day for adults and children over 2 years of age 1.
Dosing Details
Chymoral Forte is an oral preparation containing alpha-chymotrypsin, a proteolytic enzyme with anti-inflammatory properties. The FDA-approved dosing is straightforward:
- Frequency: 4 times daily
- Dose: 6 drops per administration
- Age range: Suitable for ages 2 to adult
Clinical Applications
Chymoral Forte has been studied in several clinical contexts:
- In burn patients, it has been shown to modulate inflammatory cytokines (IL-1beta and IL-6), potentially reducing the severity of the inflammatory phase 2
- Studies have demonstrated its effects on acute-phase proteins following burn injury, reflecting anti-inflammatory activity 3
- It has been evaluated in lumbar disc prolapse treatment, though with limited benefits over placebo 4
Administration Considerations
- The medication should be taken consistently throughout the day to maintain therapeutic levels
- The oral drops formulation allows for easy administration
- No specific timing relative to meals is specified in the FDA labeling
Monitoring
While specific monitoring parameters are not outlined in the available evidence for Chymoral Forte, clinicians should:
- Assess clinical response to therapy
- Monitor for any adverse effects
- Evaluate the need for continued therapy based on symptom improvement
Important Considerations
- The evidence base for Chymoral Forte is limited compared to many other anti-inflammatory medications
- The medication appears to have a favorable safety profile based on available studies
- No specific drug interactions or contraindications are mentioned in the available evidence
It's worth noting that while Chymoral Forte has been studied in specific conditions like burns and lumbar disc prolapse, the overall quality of evidence supporting its use is modest compared to other anti-inflammatory agents.