What is the next step for investigating pelvic and groin pain?

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Last updated: October 2, 2025View editorial policy

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Next Steps for Investigating Pelvic and Groin Pain

For patients with pelvic and groin pain, a pelvic ultrasound (transvaginal and transabdominal) should be the initial imaging study of choice, followed by MRI pelvis if the ultrasound is inconclusive or nondiagnostic.

Initial Imaging Approach

Pelvic Ultrasound (First-Line)

  • Combined transabdominal and transvaginal ultrasound is the initial imaging study of choice for evaluating pelvic and groin pain 1
  • Ultrasound can provide detailed anatomic information about:
    • Uterine size and endometrial canal distension
    • Fallopian tube dilation
    • Ovaries and adnexal masses
    • Pelvic fluid collections 1
  • Doppler evaluation should be included as a standard component to assess:
    • Internal vascularity of pelvic structures
    • Distinguish fluid and cysts from solid tissue
    • Evaluate for vascular abnormalities such as pelvic venous disorders 1

When Ultrasound Is Inconclusive

MRI Pelvis (Second-Line)

  • MRI is widely regarded as the problem-solving imaging examination of choice when ultrasound findings are nondiagnostic or inconclusive 1
  • MRI provides superior soft tissue contrast and can identify:
    • Pelvic inflammatory disease
    • Adhesive disease (visualized as low-signal bands between structures)
    • Pelvic venous disorders
    • Peritoneal inclusion cysts 1
  • When clinically indicated, gadolinium-based IV contrast is preferred 1

CT Abdomen and Pelvis (Alternative Second-Line)

  • Consider CT when there is a broad differential diagnosis including both gynecologic and non-gynecologic etiologies 1
  • CT with IV contrast may be useful for:
    • Poorly localized pain
    • Suspected masses involving both abdomen and pelvis
    • Assessment of abdominal vasculature and ascites 1
  • CT has higher sensitivity than ultrasound (89% versus 70%) for urgent diagnoses in adults with abdominopelvic pain 1

Special Considerations Based on Suspected Etiology

For Deep Pelvic Pain

  • If pelvic venous disorders are suspected:
    • Ultrasound with Doppler can document engorged periuterine and periovarian veins (>8mm), low-velocity flow, and altered flow with Valsalva maneuver 1
    • MRI/MR angiography has diagnostic performance comparable to conventional venography 1
    • Time-resolved postcontrast T1-weighted MRI can directly demonstrate ovarian vein reflux 1

For Chronic Inflammatory Disease

  • Ultrasound may show pelvic fluid, hydrosalpinx, pyosalpinx, and peritoneal inclusions 1
  • MRI with T2-weighted imaging can demonstrate edema, fluid collections, and distension of endometrial canal or fallopian tubes 1
  • Postcontrast T1-weighted imaging and diffusion-weighted MRI are particularly important when infection is longstanding 1

For Suspected Musculoskeletal Causes

  • Consider stress fractures, particularly in older or osteoporotic patients:
    • Radiographs have low sensitivity for sacral and pelvic insufficiency fractures 1
    • MRI can detect stress fractures within hours of injury 1
  • For myofascial pain:
    • Ultrasound-guided trigger point injection of the iliopsoas, hip adductor, and lower abdominal muscles can be both diagnostic and therapeutic 2
    • The iliopsoas muscle is commonly affected in patients with chronic pelvic pain 2

For Neural Origin Pain

  • Consider involvement of lateral femoral cutaneous, ilioinguinal, iliohypogastric, or genitofemoral nerves 3
  • MRI can help identify nerve compression or irritation 3

For Discogenic Pain

  • Lower-level lumbar disc herniation (L4-L5 or L5-S1) can sometimes present as groin pain 4
  • MRI of the lumbar spine should be considered if other imaging is negative and back symptoms are present 4

Common Pitfalls and Caveats

  • Relying solely on radiographs may miss important pathology, especially in the pelvis and sacrum due to overlying bowel gas, fecal material, and soft tissue 1
  • Overreliance on nonspecific MRI findings can lead to misdiagnosis of stress fractures as more aggressive lesions 1
  • When adhesive disease is suspected, real-time dynamic ultrasound or cine clips may document abnormal adherence or lack of mobility of structures, but adhesive disease remains notoriously difficult to confirm nonoperatively 1
  • In patients with suspected bone pathology, biopsy should only be performed at a reference center by the surgeon who will carry out the definitive tumor resection or a radiologist member of the team 1

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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