Recommended Approach for Evaluating Hoarseness (Dysphonia)
Clinicians should perform laryngoscopy, or refer to a clinician who can perform laryngoscopy, when hoarseness fails to resolve or improve within 4 weeks or irrespective of duration if a serious underlying cause is suspected. 1
Initial Assessment
- Identify dysphonia in patients presenting with altered voice quality, pitch, loudness, or vocal effort that impairs communication or reduces quality of life 1
- Conduct a targeted history and physical examination to identify underlying causes and factors that modify management 1
- Document specific voice characteristics, duration of symptoms, and associated symptoms 2
Expedited Evaluation Factors
Expedited laryngeal evaluation is indicated in patients with any of these risk factors:
- Recent surgical procedures involving the head, neck, or chest 1
- Recent endotracheal intubation 1
- Presence of concomitant neck mass 1
- Respiratory distress or stridor 1
- History of tobacco or alcohol abuse 1, 2
- Professional voice users (singers, teachers, public speakers) 1
- Hoarseness with hemoptysis, dysphagia, odynophagia, otalgia, or airway compromise 1
- Unexplained weight loss 1
- Progressive worsening of hoarseness 1
- Immunocompromised host 1
- Possible aspiration of a foreign body 1
- Hoarseness in a neonate 1
- Unresolving hoarseness after surgery 1
Diagnostic Approach
Timing of Laryngoscopy
- Clinicians may perform diagnostic laryngoscopy at any time in a patient with dysphonia (option) 1
- Laryngoscopy is required when hoarseness fails to resolve within 4 weeks (updated from previous 3-month recommendation in 2009 guideline) 1
- Immediate laryngoscopy is indicated regardless of duration if a serious underlying cause is suspected 1
Imaging Considerations
- Do not obtain CT or MRI for patients with a primary voice complaint prior to visualization of the larynx 1
- When imaging is needed after laryngoscopy, CT with contrast is the imaging of choice to evaluate laryngeal tumors and find the etiology of vocal cord paralysis 3
- For left vocal cord paralysis evaluation, CT neck must cover the aorticopulmonary window 3
Treatment Approach
Medications to Avoid for Empiric Treatment
- Do not routinely prescribe antibiotics to treat dysphonia 1
- Do not prescribe antireflux medications to treat isolated dysphonia based on symptoms alone without laryngoscopy 1
- Do not routinely prescribe corticosteroids for patients with dysphonia prior to visualization of the larynx 1
Appropriate Interventions
- Perform diagnostic laryngoscopy before prescribing voice therapy and communicate results to the speech-language pathologist 1
- Voice therapy is effective for improving voice quality in patients with nonorganic dysphonia and for treating many benign pathologic vocal cord lesions 4, 5
- Consider surgery for conditions amenable to surgical intervention (suspected malignancy, symptomatic benign vocal fold lesions that don't respond to conservative management, glottic insufficiency) 1, 2
- Offer botulinum toxin injections for dysphonia caused by spasmodic dysphonia and other types of laryngeal dystonia 1
Preventive Measures and Follow-up
- Educate patients about vocal hygiene and control/preventive measures 1, 6
- Document resolution, improvement, or worsening of symptoms after treatment or observation 1
- Voice therapy may be helpful for prophylaxis in high-risk individuals (vocalists, public speakers) 2, 4
Common Pitfalls to Avoid
- Delaying laryngoscopy beyond 4 weeks in persistent hoarseness 1
- Empiric treatment with antibiotics, corticosteroids, or proton pump inhibitors without visualization of the larynx 1, 2
- Ordering imaging studies before laryngoscopy 1
- Failing to recognize risk factors requiring expedited evaluation 1
- Overlooking occupational voice demands when developing treatment plans 1, 2