Hand, Foot, and Mouth Disease: Contagious Period and Return to School Guidelines
Children with hand, foot, and mouth disease (HFMD) are typically contagious from 1-2 days before symptoms appear until all blisters have dried and crusted over, usually 7-10 days from symptom onset, and should not return to school until they are no longer contagious.
Understanding HFMD Transmission
HFMD is a highly contagious viral illness primarily caused by enteroviruses, particularly:
- Coxsackievirus A16 (CV-A16)
- Enterovirus 71 (EV-A71)
- Coxsackievirus A6 (CV-A6)
- Coxsackievirus A10 (CV-A10) 1, 2
The virus spreads through multiple routes:
- Direct contact with respiratory secretions, saliva, or fluid from blisters 3
- Fecal-oral transmission 1
- Contact with contaminated surfaces and objects (fomites) 1
Contagious Period
The contagious period for HFMD follows a specific timeline:
- Begins 1-2 days before symptoms appear 3
- Continues throughout the acute illness phase 1
- Extends until all blisters have dried and crusted over 1
- Generally lasts 7-10 days from symptom onset 1, 3
However, it's important to note that:
- Viral shedding can continue in stool for several weeks after symptoms resolve 3
- Some studies suggest patients should be considered potentially contagious for at least 10-14 days 3
When to Return to School
Children with HFMD should not return to school until:
- Fever has resolved without fever-reducing medications 3
- All blisters/vesicles have dried and crusted over 1
- At least 7 days have passed since symptom onset 3
Preventing Transmission
To prevent spreading HFMD to others:
- Practice thorough handwashing with soap and water (alcohol-based sanitizers alone are not sufficient) 3
- Avoid close contact with others during the contagious period 3
- Use separate towels and utensils 3
- Disinfect frequently touched surfaces and toys 1
- Properly dispose of tissues containing nasal secretions 3
Special Considerations
High-Risk Settings
Those in professions with high potential for transmission should be especially cautious:
- Healthcare workers should follow strict infection control protocols 3
- Childcare providers should be particularly vigilant about handwashing and disinfection 3
Complications
While HFMD is typically self-limiting, parents should be aware of potential complications:
- Rare neurological complications like meningitis or encephalitis 1, 4
- Dehydration from painful oral ulcers limiting fluid intake 1
- Secondary bacterial infections of skin lesions 1
Treatment
Treatment is supportive and focuses on:
- Maintaining adequate hydration 1
- Pain relief with acetaminophen or ibuprofen as needed 1
- Avoiding spicy, acidic, or hot foods that may irritate mouth ulcers 5
Common Pitfalls to Avoid
Returning to school too early: Children who return before the contagious period ends can trigger outbreaks 3
Relying only on fever resolution: Some parents may send children back to school once fever resolves, but the child remains contagious until all lesions have crusted 3
Inadequate hand hygiene: Using only alcohol-based sanitizers is insufficient; soap and water are more effective against enteroviruses 3
Overlooking environmental cleaning: Enteroviruses can remain viable on surfaces for up to 28 days 3
Assuming mild cases aren't contagious: Even mild cases with few lesions can transmit the virus effectively 6