Biliary Drain Management in Palliative Care Patients
For palliative care patients with biliary drains, care should focus on maintaining adequate drainage while avoiding complications, with drainage performed at specialized centers using uncovered metal stents whenever possible, and avoiding permanent external drains if percutaneous drainage is necessary. 1
Recommended Drainage Approach
Initial Drainage Setup
- Biliary drainage in palliative care should be performed at specialized centers with expertise in biliopancreatic disease and appropriate radiological and endoscopic capabilities 1
- The goal is to drain an adequate hepatic volume (≥50%) either unilaterally or bilaterally, as determined by MRCP 1
- All drainage decisions should be discussed in a multidisciplinary team (MDT) meeting 1
Preferred Drainage Methods
- Uncovered metal stents are strongly recommended over plastic stents due to their longer patency 1
- Permanent metal stents should be reserved for cases with histological confirmation of malignancy and clear contraindications for surgery 1
- If ERCP-guided drainage is insufficient, supplementary drainage options include:
Percutaneous Drainage Considerations
- If percutaneous drainage is necessary, avoid using permanent external drains 1
- Percutaneous transhepatic biliary drainage (PTBD) carries significant risks including bacteremia, hemobilia, and liver abscess, with complication rates of approximately 23% in palliative cases 2
- Higher complication rates (36% vs 9%) and 30-day mortality (27% vs 0%) are observed in palliative cases compared to preoperative drainage 2
- Patients with very high bilirubin levels (>20 mg/dL) and advanced malignancy have particularly high risk of complications and mortality following PTBD 2
Drain Care and Maintenance
Monitoring and Complications
- Regular monitoring for signs of infection, including fever, increasing pain, or changes in drainage output 3
- Watch for complications such as:
Flushing Protocol
- While specific flushing protocols aren't detailed in the guidelines, general principles include:
Special Considerations
Combined Drainage and Nutrition
- In cases with simultaneous biliary and intestinal obstruction, specialized approaches may include:
Pitfalls to Avoid
- Avoid permanent external drains in percutaneous drainage cases, as they reduce quality of life 1
- Be vigilant about infection risk, as sepsis rates are significant (34.6%) 4
- Consider prophylactic antibiotics to decrease sepsis rates 4
- Recognize that patients with very advanced disease and high bilirubin levels (>20 mg/dL) have particularly high risk of complications and mortality 2