What are the recommended doses of Dehydroepiandrosterone (DHEA)?

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Last updated: March 21, 2025View editorial policy

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From the Research

The recommended dosage of DHEA (dehydroepiandrosterone) is 25-50 mg per day for most adults, with women starting at 25 mg and men at 50 mg, as supported by the most recent study 1.

DHEA Dosage Considerations

When considering DHEA supplementation, it's crucial to consult with a healthcare provider to determine the appropriate dosage based on individual health needs and to monitor hormone levels through blood tests. DHEA is a hormone precursor that decreases with age, and supplementation aims to restore declining levels.

Potential Benefits and Risks

Potential benefits of DHEA supplementation include improved energy, mood, and sexual function, particularly in older adults or those with adrenal insufficiency. However, DHEA is not recommended for everyone, especially those with hormone-sensitive conditions like certain cancers, and should not be used without medical supervision.

Administration and Monitoring

DHEA is best taken in the morning with food to minimize potential side effects like insomnia. The healthcare provider should monitor the patient's response to DHEA and adjust the dosage as needed to minimize side effects and maximize benefits.

Evidence-Based Recommendations

The recommended dosage is based on the most recent and highest-quality study available, which suggests that DHEA supplementation may have benefits for certain individuals, but more research is needed to fully understand its effects 1.

Key Points

  • DHEA dosage: 25-50 mg per day
  • Women: start with 25 mg
  • Men: start with 50 mg
  • Consult with a healthcare provider before starting DHEA supplementation
  • Monitor hormone levels and adjust dosage as needed
  • Potential benefits: improved energy, mood, and sexual function
  • Potential risks: hormone-sensitive conditions, side effects like insomnia

References

Research

Should Dehydroepiandrosterone Be Administered to Women?

The Journal of clinical endocrinology and metabolism, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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