Cardiac Arrest Management Protocol
The management of cardiac arrest requires a structured approach following the chain of survival, which includes prompt recognition, early CPR, rapid defibrillation, effective advanced life support, and integrated post-arrest care to optimize outcomes. 1
Immediate Response and Recognition
- Cardiac arrest should be assumed in any collapsed and unresponsive individual 2
- Seizure-like activity and abnormal breathing or gasping must be considered as signs of cardiac arrest until proven otherwise 2
- Immediately activate the emergency medical response system and call for additional assistance 2
High-Quality CPR
- Begin hands-only (compression-only) CPR immediately if the patient is unresponsive and not breathing normally 2
- Push hard (at least 5 cm/2 inches deep) and fast (100-120 compressions/minute), allowing complete chest recoil 2
- Minimize interruptions in chest compressions to maintain perfusion 2
- Switch compressors every 2 minutes or sooner if fatigued to maintain effective compressions 2
- For patients without advanced airway, use a 30:2 compression-to-ventilation ratio 2
- Avoid excessive ventilation as it can impede venous return and decrease cardiac output 2
Defibrillation
- Apply an automated external defibrillator (AED) or manual defibrillator as soon as possible while CPR continues 2
- Stop CPR only for rhythm analysis and shock delivery if indicated 2
- Resume CPR immediately after shock delivery for 2 minutes before reassessing rhythm 2
- If no shock is delivered, continue CPR and life support measures until the patient becomes responsive or a non-cardiac etiology is established 2
Advanced Airway Management
- Establish an advanced airway (endotracheal intubation or supraglottic airway device) 2
- Confirm correct placement using waveform capnography 2
- After advanced airway placement, provide 1 breath every 6 seconds (10 breaths/min) with continuous chest compressions 2
- Monitor PETCO2 (typically 35-40 mm Hg) to assess CPR quality and detect return of spontaneous circulation 2
Medication Administration
- For shock-refractory ventricular fibrillation/pulseless ventricular tachycardia (VF/pVT), consider either amiodarone or lidocaine 2
- Amiodarone IV/IO dose: First dose 300 mg bolus, second dose 150 mg 2
- Lidocaine IV/IO dose: First dose 1-1.5 mg/kg, second dose 0.5-0.75 mg/kg 2
- Consider vasopressors according to standard ACLS protocols 2
Identify and Treat Reversible Causes
- Search for and treat the "H's and T's" of cardiac arrest 2:
- Hypovolemia, hypoxia, hydrogen ion (acidosis), hypo/hyperkalemia, hypothermia
- Tension pneumothorax, tamponade (cardiac), toxins, thrombosis (coronary or pulmonary)
Return of Spontaneous Circulation (ROSC) Indicators
- Presence of pulse and blood pressure 2
- Abrupt sustained increase in PETCO2 (typically >40 mm Hg) 2
- Spontaneous arterial pressure waves with intra-arterial monitoring 2
Post-Cardiac Arrest Care
- Optimize cardiopulmonary function and vital organ perfusion 2
- Transport to an appropriate hospital with comprehensive post-cardiac arrest care capabilities 2
- Control body temperature to optimize survival and neurological recovery 2
- Consider therapeutic hypothermia (32-34°C) for comatose survivors 2
- Identify and treat acute coronary syndromes 2
- Optimize mechanical ventilation to minimize lung injury 2
- Elevate head of bed 30° if tolerated to reduce cerebral edema, aspiration, and ventilator-associated pneumonia 2
- Titrate inspired oxygen to achieve arterial oxygen saturation of 94% to avoid potential oxygen toxicity 2
- Target ventilation to achieve PETCO2 of 35-40 mm Hg or PaCO2 of 40-45 mm Hg 2
Team Approach and Quality Improvement
- Implement performance-focused debriefing for resuscitation team members after in-hospital cardiac arrest 2
- Develop system-wide plans for proactive treatment of cardiac arrest patients 2
- Consider transport to specialized centers with higher cardiac arrest case volumes for improved outcomes 2
Special Considerations
- For cardiac arrest on a sports field, perform initial CPR and defibrillation at the location of collapse 2
- Only transfer the patient after careful consideration, as external chest compression during transit may be less effective 2
- For hypothermic patients, continue CPR until rewarming is achieved 1
By following this structured protocol for cardiac arrest management, healthcare providers can optimize the chances of successful resuscitation and improve patient outcomes.