Initial Approach to Managing Knee Pain with Observable Signs
The optimal management of knee pain requires a combination of non-pharmacological and pharmacological treatment modalities tailored according to knee risk factors, general risk factors, pain intensity, signs of inflammation, and degree of structural damage. 1
Initial Assessment
- Perform a biopsychosocial assessment including physical status, activities of daily living, participation, mood, and health education needs 1
- Evaluate knee-specific factors including:
- Obtain radiographs as the initial imaging study for chronic knee pain, including:
- At least one frontal projection (anteroposterior, Rosenberg, or tunnel view)
- Tangential patellar view
- Lateral view of the affected knee 1
Management Based on Clinical Presentation
For Osteoarthritis (most common cause in patients ≥45 years)
First-line non-pharmacological interventions:
Pharmacological management:
- Start with paracetamol (acetaminophen) as first-line oral analgesic 1
- If inadequate response, consider topical NSAIDs or capsaicin 1
- For patients unresponsive to paracetamol, consider oral NSAIDs (e.g., naproxen) at the lowest effective dose 1, 4
- For acute flares with effusion, consider intra-articular corticosteroid injection 1
For Patellofemoral Pain (common in younger, active individuals)
- Hip and knee strengthening exercises combined with:
- Education on activity modification and load management 1, 3
For Meniscal Tears
- Conservative management with exercise therapy for 4-6 weeks for most tears, especially degenerative tears in patients >40 years 3
- Surgical referral only for severe traumatic tears with mechanical symptoms that don't respond to conservative care 3
Special Considerations
- Rule out referred pain from hip or lumbar spine if knee radiographs are unremarkable 1
- Consider additional imaging (MRI) only when initial radiographs are normal or show joint effusion and symptoms persist despite appropriate initial management 1
- Be aware that dangerous outcomes (fracture, thrombosis) are rare; knee pain in general practice is mainly associated with chronic problems 5
- Age-related patterns can help guide diagnosis:
- Teenage girls/young women: more likely to have patellar tracking problems
- Teenage boys/young men: more likely to have extensor mechanism problems
- Older adults: more likely to have osteoarthritis 6
Common Pitfalls to Avoid
- Ordering MRI without recent radiographs (occurs in approximately 20% of chronic knee pain cases) 1
- Recommending surgical intervention for degenerative meniscal tears before adequate trial of conservative management 3, 7
- Failing to consider weight management as a core component of treatment for patients with knee osteoarthritis 1
- Underutilizing non-pharmacological approaches, which should be the foundation of management for most knee pain conditions 1, 3