How do you manage an abnormal pulse?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 5, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of Abnormal Pulse

The management of an abnormal pulse requires a systematic approach including ECG documentation, identification of the underlying rhythm, and treatment based on the specific arrhythmia diagnosed. 1

Initial Assessment

  • Physical examination may reveal an abnormal pulse through irregular pulse rhythm, irregular jugular venous pulsations, and variation in the loudness of the first heart sound 1
  • Pulse deficit (difference between apical and peripheral pulse rates) should be assessed when irregular rhythm is detected 2
  • Determine if the patient is hemodynamically stable or unstable, as this will guide immediate management decisions 1

Diagnostic Evaluation

Minimum Required Testing

  • Electrocardiogram (ECG): Essential for documenting the arrhythmia - at least single-lead ECG recording during the dysrhythmia 1

  • History and physical examination to determine:

    • Presence and nature of symptoms associated with the arrhythmia 1
    • Clinical type (first episode, paroxysmal, persistent, or permanent) 1
    • Onset, frequency, duration, precipitating factors, and modes of termination 1
    • Response to previous treatments 1
    • Presence of underlying heart disease or reversible conditions (e.g., hyperthyroidism, alcohol consumption) 1, 3
  • Blood tests: Thyroid function tests, especially for first episodes, difficult rate control, or unexpected recurrence after cardioversion 1

Additional Testing Based on Clinical Presentation

  • Holter monitoring or event recording if:

    • Diagnosis of arrhythmia type is unclear 1
    • Episodes are infrequent (event recorder preferred) 1
    • Evaluation of rate control is needed 1
  • Echocardiogram to identify:

    • Valvular heart disease 1
    • Atrial and ventricular size and function 1
    • Pulmonary hypertension 1
    • Left ventricular hypertrophy 1
    • Pericardial disease 1
  • Chest radiograph when clinical findings suggest pulmonary or vascular abnormalities 1

  • Exercise testing for:

    • Evaluating rate control in permanent atrial fibrillation 1
    • Reproducing exercise-induced arrhythmias 1
    • Excluding ischemia before treatment with certain antiarrhythmic drugs 1
  • Transesophageal echocardiography to:

    • Identify left atrial thrombus 1
    • Guide cardioversion 1
  • Electrophysiological study to:

    • Clarify mechanism of wide-QRS-complex tachycardia 1
    • Identify predisposing arrhythmias 1
    • Locate sites for ablation 1

Management Approach

For Unstable Patients

  • Immediate synchronized cardioversion for unstable tachycardia 1
  • Atropine for unstable bradycardia 3

For Stable Patients

Management of Specific Arrhythmias

  1. Atrial Fibrillation/Flutter:

    • Two fundamental approaches: restore and maintain sinus rhythm OR allow AF to continue with controlled ventricular rate 1
    • Consider anticoagulation to prevent thromboembolism 1
    • Review medication history to identify potential drug-induced causes 1
  2. Premature Atrial Contractions (PACs):

    • Eliminate reversible causes (electrolyte abnormalities, hyperthyroidism) 3
    • For symptomatic PACs: beta blockers; consider ablation in selected cases 3
  3. Premature Ventricular Contractions (PVCs):

    • Exclude reversible causes (electrolyte abnormalities, hyperthyroidism, stimulant use) 3
    • Echocardiogram to detect underlying heart disease 3
    • Treatment options: beta blockers, non-dihydropyridine calcium channel blockers, or antiarrhythmics 3
    • Consider ablation for patients with PVCs and left ventricular dysfunction 3
  4. Supraventricular Tachycardia:

    • Stable patients: consider catheter ablation or antiarrhythmic medications 3
    • For regular wide-complex tachycardias of uncertain origin: IV adenosine may be reasonable for both diagnosis and treatment 1
  5. Ventricular Tachyarrhythmias:

    • Sotalol 1.5 mg/kg IV over 5 minutes (avoid in patients with prolonged QT) 1
    • Amiodarone 150 mg IV over 10 minutes, repeated as needed to maximum 2.2g/24 hours 1
  6. Sinus Node Dysfunction:

    • Discontinue bradycardia-causing drugs when possible 3
    • Consider pacemaker for symptomatic patients 3

Special Considerations

  • Drug-induced arrhythmias: Identify and discontinue offending drugs when possible; if not possible, reduce dose and monitor closely 1
  • Autoimmune rheumatic diseases: Be aware of specific arrhythmia patterns - sinus tachycardia in SLE, PVCs in systemic sclerosis, and conduction disorders in RA 4
  • Metabolic stress: Address underlying oxidative stress which may contribute to arrhythmogenesis 5

Follow-up

  • Regular monitoring of response to treatment 1
  • Adjustment of therapy based on symptom control and arrhythmia recurrence 1
  • Patient education regarding pulse monitoring, especially for those taking medications with potential to cause arrhythmias 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Assessing pulse deficit.

Nursing, 1993

Research

Metabolic stress, reactive oxygen species, and arrhythmia.

Journal of molecular and cellular cardiology, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.