Maximum Dose of Dramamine (Dimenhydrinate) for a 2-Year-Old Child Weighing 23 lbs
For a 2-year-old child weighing 23 pounds (approximately 10.5 kg), the maximum dose of dimenhydrinate is 13.1 mg per dose, given four times daily, with a maximum daily dose not to exceed 52.5 mg. 1
Dosage Calculation
The FDA-approved dosage for dimenhydrinate in pediatric patients is calculated based on weight:
- Recommended pediatric dose: 1.25 mg/kg of body weight 1
- For a child weighing 23 lbs (10.5 kg): 10.5 kg × 1.25 mg/kg = 13.1 mg per dose
- Administration frequency: Four times daily 1
- Maximum daily dose should not exceed 300 mg 1
Administration Considerations
- Dimenhydrinate can be administered orally or parenterally (when oral form is impractical) 1
- Doses should be spaced approximately 4 hours apart 1
- The medication may cause drowsiness in some patients 1
Safety Considerations
Toxic dose threshold: Children under 6 years who ingest at least 7.5 mg/kg of dimenhydrinate should be referred to an emergency department 2
- For this 10.5 kg child, a potentially toxic single dose would be 78.75 mg or higher
Monitor for adverse effects, which may include:
Important Warnings
- Seizures have been reported with dimenhydrinate overdose, particularly with repeated administration 3
- Children are more susceptible to developing central nervous system effects from antihistamines 2
- If the child experiences any changes in behavior other than mild drowsiness, seek medical attention 2
Alternative Management
- Before administering dimenhydrinate, consider the underlying cause of vomiting to determine if the medication is appropriate 4
- For acute gastroenteritis with vomiting, rehydration therapy may be more important than antiemetic medication 4