Would an oral steroid help with chronic bicep tendinopathy?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 6, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Oral Steroids for Chronic Bicep Tendinopathy

Oral steroids are not recommended for chronic bicep tendinopathy as they may inhibit healing, reduce tendon tensile strength, and predispose to tendon rupture, while providing only short-term relief without improving long-term outcomes. 1

Evidence Against Oral Steroids for Tendinopathy

  • Corticosteroids may inhibit healing and reduce the tensile strength of tendon tissue, potentially predisposing to spontaneous rupture 1
  • There are no evidence-based guidelines supporting the use of corticosteroids in tendinopathy, and there may be deleterious effects when used for tendon disorders 1
  • While corticosteroid injections may provide short-term relief, they do not alter long-term outcomes of pain in tendinopathy 1, 2
  • Studies show that corticosteroid effects are reversed at intermediate and long terms, with non-intervention actually being favored over corticosteroids in these timeframes 2, 3

Recommended Treatment Approach for Bicep Tendinopathy

First-Line Treatments

  • NSAIDs (oral or topical) for short-term pain relief with fewer systemic side effects when used topically 1, 4, 5
  • Rest and activity modification to avoid movements requiring repetitive wrist flexion and extension 1, 6
  • Ice therapy for 10-minute periods through a wet towel for short-term pain relief 1
  • Consider bracing or orthotics to unload the tendon 1

Second-Line Treatments

  • Physical therapy with emphasis on eccentric strengthening exercises that can help reverse degenerative changes 4, 5
  • If conservative treatment fails after 6 weeks, consider referral for surgical evaluation 1, 5

Potential Risks of Oral Steroids

  • Gastrointestinal complications including bleeding, ulceration, and perforation 1
  • Increased risk of serious adverse events with prolonged use 1, 4
  • Potential for tendon weakening and increased risk of rupture 1, 3
  • Negative effects on bone density with long-term use 7

Common Pitfalls to Avoid

  • Premature return to aggravating activities before adequate healing 1
  • Relying on corticosteroids (oral or injected) for long-term management 1, 2
  • Using multiple corticosteroid injections, which may lead to tissue weakening 1
  • Overlooking the importance of relative rest and activity modification in the treatment plan 1, 5

Alternative Treatments with Better Evidence

  • Sodium hyaluronate injections have shown better results than placebo for pain reduction in both short and long term for similar tendinopathies 2, 3
  • Surgical management (tenotomy or tenodesis) may be indicated for refractory or severe disease 6, 5

In conclusion, while oral steroids might temporarily reduce pain in bicep tendinopathy, the potential risks outweigh the benefits, particularly given their lack of long-term efficacy and potential to cause tendon weakening and rupture. A more conservative approach using NSAIDs, rest, ice, and physical therapy should be attempted first, with surgical options considered for refractory cases.

References

Guideline

Risks and Treatment of Tennis Elbow

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Corticosteroid and other injections in the management of tendinopathies: a review.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2011

Guideline

Tratamiento Farmacológico para Tendinitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Long head of the biceps tendinopathy: diagnosis and management.

The Journal of the American Academy of Orthopaedic Surgeons, 2010

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.