From the Research
There is currently no established direct link between semaglutide and tinnitus as a common side effect, as evidenced by the most recent and highest quality study available 1. If you're experiencing tinnitus while taking semaglutide, you should consult your healthcare provider rather than discontinuing the medication on your own. Semaglutide primarily works by mimicking GLP-1 hormones to regulate blood sugar and reduce appetite, with common side effects typically involving gastrointestinal symptoms like nausea, vomiting, and diarrhea. Some key points to consider about semaglutide include:
- Its efficacy in glycemic control and weight reduction in type 2 diabetes mellitus (T2DM) 2
- Its safety profile, which is consistent with the GLP-1RA drug class, with a low risk of hypoglycemia and most common adverse events being gastrointestinal 1
- Its potential benefits in reducing cardiovascular risk factors, as demonstrated in cardiovascular outcome trials (CVOTs) 3, 4 Tinnitus (ringing or buzzing in the ears) can have many causes including age-related hearing loss, ear injuries, circulatory system disorders, or other medications. If you develop tinnitus while on semaglutide, your doctor might evaluate whether it's related to the medication, another condition, or potentially an indirect effect through changes in blood pressure or blood sugar levels. They may recommend continuing the medication while monitoring symptoms, adjusting the dose, or considering alternative treatments depending on your specific situation and the severity of your symptoms. It's essential to follow the guidance of your healthcare provider to ensure the best possible outcome in terms of morbidity, mortality, and quality of life.