What are the recommended management strategies for bed sore (pressure ulcer) treatment?

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Last updated: October 7, 2025View editorial policy

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Management Strategies for Pressure Ulcers (Bed Sores)

Effective management of pressure ulcers requires a combination of debridement, appropriate dressing selection, pressure offloading, and infection control to promote healing and reduce morbidity and mortality.

Core Treatment Strategies

Wound Cleaning and Debridement

  • Clean the wound regularly with water or saline to remove debris and create an optimal healing environment 1
  • Perform regular debridement with a scalpel to remove necrotic tissue, which is necessary for proper wound healing 1
  • Surgical debridement is particularly important for infected pressure ulcers to remove all necrotic tissue 1

Dressing Selection

  • Use hydrocolloid or foam dressings to reduce wound size and promote healing 1
  • Hydrocolloid dressings are better than gauze dressings for reducing wound size (low-quality evidence) 1, 2
  • Foam dressings (hydrocellular or polyurethane) have similar effectiveness to hydrocolloid dressings for complete wound healing 1, 2
  • Control exudate to maintain a moist wound environment; a sterile, inert protective dressing is usually sufficient 1

Nutritional Support

  • Provide protein or amino acid supplementation to reduce wound size, especially in nutritionally deficient patients 1
  • Nutritional supplementation should be used in conjunction with standard therapies such as dressings or support surfaces 1
  • Evidence does not show benefit of vitamin C supplementation compared with placebo 1

Pressure Offloading

  • Implement complete pressure offloading from the affected area to minimize trauma to the ulcer site 1, 3
  • Consider specialized support surfaces for pressure redistribution 4
  • Air-fluidized beds may be superior to standard hospital beds for reducing pressure ulcer size 1, 4

Adjunctive Therapies

Electrical Stimulation

  • Use electrical stimulation as adjunctive therapy to accelerate wound healing for stage 2 to 4 ulcers (moderate-quality evidence) 1
  • Be aware that skin irritation is the most common adverse effect, with frail elderly patients being more susceptible to adverse events 1

Infection Management

  • Assess for signs of infection such as increasing pain, erythema, warmth, or purulent drainage 1
  • For infected pressure ulcers, use antibiotic therapy directed against both Gram-positive and Gram-negative facultative organisms as well as anaerobes, as these infections are typically polymicrobial 1
  • Consider local antimicrobial therapy for superficial infections and systemic antibiotics for deeper or more severe infections 1, 5

Other Therapies with Limited Evidence

  • Topical negative pressure therapy may hasten healing of post-operative wounds, but effectiveness and cost-effectiveness remain to be established 1
  • Systemic hyperbaric oxygen therapy may increase healing incidence, though further studies are needed 1
  • Evidence is insufficient for platelet-derived growth factor (becaplermin), bioengineered skin products, and other growth factors 1
  • There is insufficient evidence to recommend silver-containing dressings or other antiseptic products in routine management 1, 5

Special Considerations

Monitoring and Assessment

  • Regularly assess the wound for signs of healing or deterioration 3
  • If the pressure ulcer is not showing signs of healing within 6 weeks despite optimal management, evaluate for vascular compromise 3
  • For patients with heel ulcers, be particularly vigilant about infection control and vascular assessment 3

Prevention of Recurrence

  • Develop a prevention plan once the ulcer is healed to avoid recurrence 3
  • Consider the patient's overall health status and comorbidities that may affect healing, especially in elderly patients 1

Cautions and Pitfalls

  • Avoid using advanced support surfaces like alternating-air and low-air-loss beds without clear indication, as evidence for their effectiveness is limited and they add unnecessary costs 1
  • Be aware that dehiscence is a common complication following surgical repair of pressure ulcers, especially when bone is removed or with ischial ulcers 1
  • Patients with spinal cord injury may have a higher rate of recurrent pressure ulcers after surgical closure 1
  • Do not rely solely on intermediate outcomes like reduction in wound size, as the relationship between reduction in wound size and eventual complete healing is not well-defined 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Dressings and topical agents for treating pressure ulcers.

The Cochrane database of systematic reviews, 2017

Guideline

Treatment of Stage 2 Left Heel Pressure Injury with Necrotic Tissue

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Antibiotics and antiseptics for pressure ulcers.

The Cochrane database of systematic reviews, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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