What causes a firm lump on the plantar (sole of the foot) surface of the foot?

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Last updated: March 22, 2025View editorial policy

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Differential Diagnosis for a Firm Lump on the Plantar Surface of the Foot

  • Single Most Likely Diagnosis
    • Plantar wart: This is the most common cause of a firm lump on the plantar surface of the foot. It is caused by the human papillomavirus (HPV) and can be painful, especially when pressure is applied.
  • Other Likely Diagnoses
    • Plantar callus: A thickened area of skin that can develop due to repeated pressure or friction on the plantar surface of the foot.
    • Plantar fibroma: A benign growth of fibrous tissue that can occur on the plantar surface of the foot, often causing pain and discomfort.
    • Morton's neuroma: A condition where the tissue around a nerve in the foot becomes thickened, causing pain and a lump-like sensation.
  • Do Not Miss Diagnoses
    • Plantar melanoma: A type of skin cancer that can present as a firm lump on the plantar surface of the foot. It is essential to consider this diagnosis to ensure early detection and treatment.
    • Deep tissue infection (e.g., abscess or cellulitis): Infections can cause firm lumps on the plantar surface of the foot and require prompt medical attention to prevent serious complications.
  • Rare Diagnoses
    • Plantar ganglion cyst: A rare, benign cyst that can develop on the plantar surface of the foot, often causing pain and discomfort.
    • Lipoma: A rare, benign tumor composed of fat tissue that can occur on the plantar surface of the foot.
    • Plantar schwannoma: A rare, benign tumor of the nerve tissue that can occur on the plantar surface of the foot, often causing pain and discomfort.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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