What are the recommended approaches for arthritis management?

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Last updated: October 7, 2025View editorial policy

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Recommended Approaches for Arthritis Management

The optimal management of arthritis requires a comprehensive, multimodal approach including exercise, weight management, self-management programs, appropriate orthoses, and pharmacologic interventions tailored to the specific type of arthritis and affected joints. 1

Core Interventions for All Arthritis Patients

Exercise Therapy

  • Strong recommendation for regular exercise programs for all patients with osteoarthritis (OA) of the hand, hip, and knee 1
  • Exercise options should include:
    • Walking, strengthening exercises, neuromuscular training, and aquatic exercise for knee and hip OA 1
    • Supervised exercise programs yield better outcomes than unsupervised ones 1
    • Tai chi is strongly recommended for all OA patients 1
  • Exercise improves disease activity, reduces symptoms like pain and fatigue, and enhances function and mental health 2, 3

Weight Management

  • Strong recommendation for weight loss in patients with knee and/or hip OA who are overweight or obese 1
  • Weight management is a key preventive strategy in the absence of disease-modifying agents 1

Self-Management Programs

  • Strong recommendation for self-efficacy and self-management programs 1
  • These programs can significantly improve physical function and pain management 1
  • Should include education about arthritis, coping strategies, and activity pacing 1

Joint-Specific Interventions

Hand Arthritis Management

  • Strong recommendation for first carpometacarpal (CMC) joint orthoses (neoprene or rigid) 1
  • Conditional recommendation for orthoses for other hand joints 1
  • Conditional recommendation for kinesiotaping for first CMC OA 1
  • Topical NSAIDs, intraarticular steroid injections, and chondroitin sulfate are conditionally recommended for hand OA 1

Knee Arthritis Management

  • Strong recommendation for tibiofemoral bracing for tibiofemoral OA 1
  • Conditional recommendation for patellofemoral bracing for patellofemoral OA 1
  • Strong recommendation for cane use to improve mobility 1
  • Strong recommendation for topical NSAIDs for knee OA 1
  • Strong recommendation for intraarticular glucocorticoid injections 1
  • Conditional recommendation for topical capsaicin 1

Hip Arthritis Management

  • Strong recommendation for intraarticular glucocorticoid injections 1
  • Walking aids (canes) strongly recommended to improve mobility and function 1

Pharmacologic Management

First-Line Options

  • Strong recommendation for topical NSAIDs for knee OA (lower systemic exposure) 1
  • Strong recommendation for oral NSAIDs for hand, knee, and hip OA 1
    • Naproxen has demonstrated efficacy in controlling joint swelling, reducing morning stiffness, and improving mobility in OA patients 4
    • Begin with lowest effective dose to minimize gastrointestinal and cardiovascular risks 1

Second-Line Options

  • Conditional recommendation for acetaminophen (lower efficacy but safer profile for some patients) 1
  • Conditional recommendation for duloxetine for pain management 1
  • Conditional recommendation for tramadol when other options have failed 1

Additional Therapeutic Approaches

Mind-Body Interventions

  • Conditional recommendation for yoga 1
  • Conditional recommendation for cognitive behavioral therapy 1
  • Conditional recommendation for acupuncture 1

Physical Modalities

  • Conditional recommendation for thermal modalities 1
  • Conditional recommendation for massage therapy 1
  • Conditional recommendation for balance exercises 1
  • Conditional recommendation for radiofrequency ablation for knee OA 1

Implementation Considerations

Assessment Approach

  • Evaluate for medical conditions that might impact treatment choices:
    • Hypertension, cardiovascular disease, heart failure, gastrointestinal bleeding risk, chronic kidney disease 1
    • Disease severity, surgical history, and access to services 1

Treatment Selection Algorithm

  1. Start with non-pharmacologic interventions (exercise, weight management, self-management) for all patients 1
  2. Add appropriate orthoses based on affected joints 1
  3. For persistent symptoms, add topical therapies before systemic medications 1
  4. Progress to oral medications starting with NSAIDs if no contraindications 1
  5. Consider intraarticular injections for specific joint involvement 1
  6. Add mind-body and additional integrative approaches as needed 1

Common Pitfalls to Avoid

  • Focusing solely on pharmacologic management without addressing exercise and weight management 1
  • Failing to provide specific exercise recommendations and supervision 1, 5
  • Not addressing psychosocial aspects of chronic pain management 1
  • Using opioids before exhausting safer alternatives 1
  • Not tailoring interventions to the specific joint(s) affected 1

Special Considerations

  • Patients may experience additional symptoms such as mood disorders, altered sleep, and chronic widespread pain that require addressing as part of the treatment plan 1
  • When choosing pharmacologic therapies, begin with treatments having the least systemic exposure or toxicity 1
  • Regular monitoring and adjustment of the treatment plan is necessary as arthritis is a progressive condition 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Managing arthritis with exercise.

Geriatric nursing (New York, N.Y.), 2001

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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