Management Strategies for Tension Headaches
For tension headache management, ibuprofen 400 mg or acetaminophen 1000 mg are recommended as first-line treatments for acute episodes, while amitriptyline is suggested for prevention of chronic tension-type headache. 1, 2
Acute Treatment Options
- Ibuprofen 400 mg is recommended for short-term treatment of tension-type headache, showing statistically significant improvement in pain-free response at 2 hours 1, 2, 3
- Acetaminophen 1000 mg is an equally effective alternative for acute treatment, also demonstrating significant improvement in pain-free response at 2 hours 1, 2, 4
- For patients with moderate to severe tension headache, ibuprofen 400 mg provides an NNT of 14 for being pain-free at 2 hours compared to placebo 3
- The use of rescue medication is lower with ibuprofen 400 mg than with placebo, with an NNTp of 8.9 3
- Caffeine-containing preparations may provide slightly superior relief but should be used cautiously to avoid headache chronification 5
Preventive Treatment
- Amitriptyline is suggested for the prevention of chronic tension-type headache (occurring 15 or more days per month) 1, 2
- Typical effective doses of amitriptyline range from 50-100 mg daily, which significantly reduces monthly headache days 2, 6
- When prescribing amitriptyline, be aware of anticholinergic adverse effects, especially in older patients and those with cardiac comorbidities 2
- Cognitive-behavioral therapy has shown comparable or even superior outcomes to amitriptyline in some studies, with a 56% reduction in headache index compared to 27% with amitriptyline 6
- Botulinum/neurotoxin injections are not recommended for the prevention of chronic tension-type headache 1
Non-Pharmacological Approaches
- Physical therapy and aerobic exercise are recommended as management options for tension-type headache 2
- Relaxation therapies with EMG biofeedback have shown efficacy rates of 40-50% for chronic tension-type headache 5, 7
- Cognitive-behavioral therapy, particularly when administered in a home-based treatment protocol, has demonstrated significant improvement in headache activity 6
- Non-pharmacological approaches should be considered particularly for patients who:
Treatment Algorithm
For acute tension headache episodes:
For chronic tension-type headache (≥15 headache days/month):
For all patients with frequent tension headaches: