What should I do if I took Plan B (levonorgestrel) and missed my menstruation?

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Management of Missed Menstruation After Taking Plan B (Levonorgestrel)

A pregnancy test should be performed if you miss your period after taking Plan B (levonorgestrel), as this is the most important first step to determine if the emergency contraception was effective. 1, 2

Initial Assessment

  • Perform a pregnancy test first to rule out pregnancy, which is the most common concern after missed menstruation following Plan B use 1
  • Plan B works by preventing or delaying ovulation and is approximately 85% effective when taken within 72 hours of unprotected intercourse 3, 2
  • Menstrual changes are a common side effect of levonorgestrel emergency contraception and can include early, late, heavier, or lighter periods 2

Understanding Plan B's Effects on Menstruation

  • Plan B may alter your menstrual cycle timing, with your next period potentially coming earlier or later than expected 2
  • You will know Plan B has been effective when you get your next period, which should come at the expected time or within a week of the expected time 2
  • If your period is delayed beyond 1 week after the expected time, pregnancy is possible and should be ruled out with a test 2

When to Seek Medical Attention

  • If your period is more than a week late after taking Plan B, perform a pregnancy test 2
  • Seek immediate medical attention if you experience severe abdominal pain, as this could indicate an ectopic pregnancy 2
  • Contact a healthcare provider if you vomited within 2 hours of taking Plan B, as you may need to repeat the dose 2

Follow-up Recommendations

  • If pregnancy test is negative and period is still absent:

    • Wait another week and retest if period doesn't return 1
    • Consider evaluation for other causes of amenorrhea if period remains absent for more than 6 weeks 1
  • If pregnancy test is positive:

    • Schedule an appointment with a healthcare provider for prenatal care 1
    • Be aware that Plan B will not affect an existing pregnancy 2

Important Considerations

  • Plan B is not intended for regular contraception and is less effective than regular birth control methods 2
  • Consider discussing more reliable long-term contraceptive options with your healthcare provider 3
  • Remember that Plan B does not protect against sexually transmitted infections 2

Common Side Effects of Plan B

  • Besides menstrual changes, other common side effects include nausea, lower abdominal pain, tiredness, headache, dizziness, and breast tenderness 2
  • These side effects are typically mild and resolve on their own within a few days 2
  • The effectiveness of Plan B may be reduced if you are taking certain medications including efavirenz (HIV medication), rifampin (tuberculosis treatment), or medications for seizures 2

Remember that while Plan B is effective emergency contraception, it should not replace regular contraceptive methods, which are more reliable for ongoing pregnancy prevention 2, 4.

References

Guideline

Evaluation of Missed Menstrual Period

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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