Management of Food Allergy
The cornerstone of food allergy management is strict avoidance of the specific allergen, prompt recognition of allergic reactions, and immediate treatment with epinephrine for severe reactions. 1
Diagnosis and Initial Evaluation
- Refer patients with suspected food allergy to an allergist for comprehensive evaluation including skin prick tests and/or serum-specific IgE tests to identify potential food allergens 1, 2
- A positive test result alone is insufficient for diagnosis - clinical correlation with history is required 2
- In some cases, oral food challenges may be necessary to confirm the diagnosis under medical supervision 1
Primary Management Strategy
Allergen Avoidance
- Complete avoidance of the identified allergen is the first-line treatment for food allergy 1, 2
- Educate patients and caregivers on:
Nutritional Considerations
- Provide nutritional counseling and regular growth monitoring, especially for children with food allergies 1, 2
- When eliminating major food groups, ensure adequate nutritional intake through appropriate substitutions 2
- For infants with food allergies who are exclusively breastfed, the allergen may need to be eliminated from the mother's diet 4
Emergency Management
Medications and Action Plan
- Prescribe epinephrine autoinjectors for all patients with IgE-mediated food allergy, especially those with:
- Epinephrine dosing:
- Adults and children ≥30 kg: 0.3 to 0.5 mg IM in anterolateral thigh
- Children <30 kg: 0.01 mg/kg IM in anterolateral thigh (maximum 0.3 mg) 5
- Antihistamines are appropriate for managing mild, non-severe allergic reactions 1
- Create and provide a written emergency action plan that includes:
- Recognition of symptoms of allergic reactions
- Instructions for epinephrine administration
- Emergency contact information 1
Management of Anaphylaxis
- Administer epinephrine immediately for anaphylaxis - delayed administration has been implicated in fatalities 1, 5
- Epinephrine doses may need to be repeated every 5-15 minutes if symptoms persist 1
- After treatment for anaphylaxis, patients should:
- Be observed for 4-6 hours in a medical facility
- Be discharged with two doses of epinephrine
- Have a follow-up plan for further evaluation 1
Patient Education and Quality of Life
- Provide age-appropriate education on:
- Allergen avoidance strategies
- Recognition of allergic symptoms
- Proper use of epinephrine autoinjectors 1
- Address quality of life concerns, as food allergy can increase anxiety for patients and families 1
- For adolescents and young adults (high-risk group for fatal anaphylaxis), provide specific counseling on risk-taking behaviors and transition of responsibility 1
- Consider referral to support resources such as the Food Allergy and Anaphylaxis Network (www.foodallergy.org) 1
Special Considerations
Schools and Community Settings
- Provide documentation for schools (e.g., food allergy emergency action plan, Section 504 plans) 1
- Educate school staff on recognition and management of allergic reactions 1
- Ensure epinephrine is available and that staff are trained in its use 1
Vaccines
- MMR and MMRV vaccines are safe for children with egg allergy, even those with severe reactions 1
- Most patients with egg allergy can receive influenza vaccines under appropriate supervision 1
Follow-up Care
- Regular follow-up with an allergist is recommended to:
Emerging Treatments
- While promising, oral immunotherapy, sublingual immunotherapy, and epicutaneous immunotherapy are still considered investigational and not recommended for routine clinical practice 1, 6
- These approaches carry the risk of severe reactions and should only be considered in specialized centers 1
Common Pitfalls to Avoid
- Failing to distinguish between true food allergy and food intolerance, leading to unnecessary dietary restrictions 2
- Neglecting nutritional needs when implementing elimination diets 2
- Underutilization of epinephrine - it is vastly underprescribed and underused by healthcare providers and patients 1
- Relying solely on antihistamines for treatment of anaphylaxis instead of epinephrine 1
- Implementing overly restrictive diets based solely on sensitization (positive test) without clinical symptoms 1