Treatment of Acute Bronchitis
For patients with acute bronchitis, routine treatment with antibiotics is not justified and should not be offered, as acute bronchitis is primarily a viral illness. 1
Definition and Diagnosis
- Acute bronchitis is an acute respiratory infection with normal chest radiograph findings, manifested by cough with or without phlegm production lasting up to 3 weeks 1
- Respiratory viruses are the most common cause (89-95% of cases), with fewer than 10% of patients having bacterial infections 1, 2
- Pneumonia should be ruled out in patients with tachycardia (heart rate >100 beats/min), tachypnea (respiratory rate >24 breaths/min), fever (oral temperature >38°C), or abnormal chest examination findings (rales, egophony, or tactile fremitus) 1, 3
Antibiotic Treatment
- Antibiotics should not be routinely prescribed for acute bronchitis as they provide minimal benefit (reducing cough by only about half a day) while exposing patients to adverse effects 1, 4
- The presence of purulent sputum or a change in its color does not signify bacterial infection and is not an indication for antibiotics 1
- When patients expect antibiotics, clinicians should explain the decision not to use these agents and discuss the potential harm of unnecessary antibiotic use 1
Exception for Pertussis
- For confirmed or suspected pertussis (whooping cough), a macrolide antibiotic (such as erythromycin) should be prescribed 1
- Patients with pertussis should be isolated for 5 days from the start of treatment 1
- Early treatment within the first few weeks will diminish coughing paroxysms and prevent disease spread 1
Symptomatic Treatment
Bronchodilators
- β2-agonist bronchodilators should not be routinely used for cough in most patients with acute bronchitis 1
- In select adult patients with wheezing accompanying the cough, β2-agonist bronchodilators may be useful 1
- Patients with airflow obstruction at baseline may show some benefit from bronchodilators, but tremor, nervousness, and shakiness are more common in treatment groups 1
Antitussives
- Codeine or dextromethorphan may provide modest effects on severity and duration of cough in acute bronchitis 1, 5
- These central cough suppressants are recommended for short-term symptomatic relief of coughing 1, 3
Other Symptomatic Treatments
- Low-cost and low-risk actions such as elimination of environmental cough triggers and vaporized air treatments may be reasonable options 1
- There is insufficient evidence to support the use of expectorants, antihistamines, anticholinergics, NSAIDs, or inhaled/oral corticosteroids for acute bronchitis 5, 4
- Systemic corticosteroids are not justified in the treatment of acute bronchitis in healthy adults 5
Patient Education
- Inform patients that cough typically lasts 10-14 days after the office visit 1, 3
- Referring to the condition as a "chest cold" rather than bronchitis may reduce patient expectation for antibiotics 1
- Patient satisfaction with care depends more on physician-patient communication than whether an antibiotic is prescribed 1
Common Pitfalls
- Mistaking acute bronchitis for asthma exacerbation, pneumonia, or acute exacerbation of chronic bronchitis, which have different treatment approaches 5, 6
- Prescribing antibiotics based on purulent sputum, which is not an indication of bacterial infection 1, 5
- Using steroids in hopes of shortening illness duration, when evidence shows no benefit for this purpose in acute bronchitis 5
Acute bronchitis is a self-limiting disease, and treatment should focus on symptom relief and patient education rather than antibiotics or other medications that lack evidence of benefit.