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Differential Diagnosis for 86 year-old female with history of diabetes, hypertension, pulmonary hypertension, a fib on Coumadin, presenting with hypoxia, hypertension, tachycardia, and fever

  • Single most likely diagnosis
    • Pneumonia: Given the patient's age, symptoms of hypoxia, fever, and tachycardia, pneumonia is a highly likely diagnosis. The patient's history of pulmonary hypertension may also increase her susceptibility to respiratory infections.
  • Other Likely diagnoses
    • Pulmonary embolism (PE): The patient's history of atrial fibrillation and use of Coumadin increases her risk for thromboembolic events. Hypoxia, tachycardia, and hypertension are consistent with a PE.
    • Sepsis: The patient's fever, tachycardia, and hypoxia could indicate a systemic infection, which could be related to her diabetes or other comorbidities.
    • Acute coronary syndrome (ACS): Although less likely given the patient's presentation, ACS could cause hypoxia, hypertension, and tachycardia, especially in a patient with a history of hypertension.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Cardiac tamponade: The patient's history of atrial fibrillation and anticoagulation with Coumadin increases her risk for cardiac tamponade, which could present with hypoxia, tachycardia, and hypertension.
    • Massive hemoptysis: Although less likely, the patient's pulmonary hypertension and anticoagulation increase her risk for massive hemoptysis, which would be life-threatening.
    • Aortic dissection: The patient's history of hypertension increases her risk for aortic dissection, which could present with hypoxia, tachycardia, and hypertension.
  • Rare diagnoses
    • Pulmonary vasculitis: This is a rare condition that could cause hypoxia, fever, and tachycardia, but it would be less likely given the patient's presentation and history.
    • Amniotic fluid embolism: This is an extremely rare condition that would be unlikely in an 86-year-old female, but it could present with hypoxia, tachycardia, and hypertension.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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