Are there new, implanted very small pacemakers?

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Last updated: February 11, 2025View editorial policy

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From the Guidelines

Yes, there are new, implanted very small pacemakers, known as leadless pacing systems.

Details of Leadless Pacing Systems

  • These systems are a result of technical advances in the field of cardiovascular implantable electronic devices 1.
  • The development of leadless pacing systems is aimed at reducing the risk of infection associated with traditional pacemakers 1.
  • Although the idea of a biological pacemaker, which could be implanted in the heart, is also being explored, the leadless pacing system is a more immediate reality 1.
  • The leadless pacing system is a significant improvement over traditional pacemakers, offering a smaller size and potentially lower risk of complications 1.

From the Research

New Developments in Pacemaker Technology

  • Recent advances in miniaturization technologies and battery chemistries have made it possible to develop pacemakers small enough to implant within the heart, providing similar battery longevity to conventional pacemakers 2.
  • Leadless pacemakers represent a major leap in technology, emerging as an alternative to traditional systems and promising to eliminate lead and pocket-associated complications 3.
  • The Micra Transcatheter Pacing System is a miniaturized single-chamber pacemaker system that is delivered via catheter through the femoral vein and implanted directly inside the right ventricle of the heart 2.

Benefits and Limitations of Leadless Pacemakers

  • Leadless pacemakers can provide single-chamber pacing without a subcutaneous generator, reducing the risk of complications associated with traditional pacing systems 4.
  • However, leadless pacemakers also have limitations, including unknowns related to longevity and end-of-life management for the device 3.
  • Despite these limitations, leadless pacemakers have been shown to be effective in reducing the risk of complications, with device-related adverse effects observed in 6.7% of leadless pacemakers compared to 10% of traditional pacemakers with leads 5.

Future Directions in Pacemaker Technology

  • Advances in device technology are expected to include alternative energy sources and dual-chamber leadless pacing in the near future 4.
  • Biological pacemakers, generated by somatic gene transfer, cell fusion, or cell transplantation, may also provide an alternative to electronic devices, potentially expanding the therapeutic armamentarium for conduction system disorders 4.
  • Ongoing research and innovation are aimed at addressing the complications associated with traditional pacemaker systems and improving the safety and efficacy of leadless pacemakers 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The rationale and design of the Micra Transcatheter Pacing Study: safety and efficacy of a novel miniaturized pacemaker.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2015

Research

A Review of the Recent Advances of Cardiac Pacemaker Technology in Handling Complications.

Journal of long-term effects of medical implants, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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