From the Research
Relationship Between Vitamin D Deficiency and Steroid-Induced Ataxia
- There is no direct evidence in the provided studies that links Vitamin D deficiency to steroid-induced ataxia 1, 2, 3, 4, 5.
- However, a study published in 2011 found an association between glucocorticoid use and low 25-hydroxyvitamin D levels, suggesting that steroid use may be linked to Vitamin D deficiency 3.
- Another study from 2020 discussed the effects of vitamin D in the nervous system, including its interaction with steroid hormone signalling, but did not specifically address steroid-induced ataxia 5.
- A study from 2005 reported on a case of ataxia with isolated Vitamin E deficiency, which is a different vitamin deficiency, but highlights the importance of vitamin deficiencies in neurological disorders 1.
- Overall, while there is no direct evidence linking Vitamin D deficiency to steroid-induced ataxia, the provided studies suggest that vitamin D plays a role in the nervous system and that steroid use may be associated with vitamin D deficiency.
Vitamin D and Neurological Disorders
- Vitamin D has been implicated in various neurological disorders, including autism and rheumatoid arthritis 2, 4.
- A study from 2017 discussed the potential connections between vitamin D, steroids, and autism, highlighting the need for further research in this area 2.
- Another study from 2010 found that vitamin D deficiency was common in patients with rheumatoid arthritis and was associated with increased disease activity and disability 4.
Steroid Use and Vitamin D Deficiency
- The study from 2011 found that steroid use was independently associated with 25-hydroxyvitamin D deficiency, suggesting that patients on chronic steroids may be at risk of vitamin D deficiency 3.
- This association remained after multivariable adjustment, highlighting the importance of monitoring vitamin D status in patients on steroid therapy.