QRS Complex Characteristics in Different Degrees of Heart Block
First and second-degree heart blocks typically present with normal QRS complexes, while third-degree heart block often presents with wide QRS complexes, though this depends on the anatomical location of the block.
Understanding AV Block and QRS Morphology
First-Degree AV Block
- First-degree AV block is characterized by prolonged PR interval (>200 ms) with all atrial impulses conducted to the ventricles 1
- If the QRS complex is narrow, the conduction delay is usually in the AV node 1
- If the QRS is wide, the conduction delay may be either in the AV node or in the His-Purkinje system 1
- Only a His bundle electrogram can precisely locate the site of delay when QRS is wide 1
Second-Degree AV Block
- Second-degree AV block occurs when one or more atrial stimuli are not conducted to the ventricles 1
- In Mobitz type I (Wenckebach):
- In Mobitz type II:
Third-Degree (Complete) AV Block
- No atrial stimuli are conducted to the ventricles 1
- Ventricles are depolarized by an escape rhythm 1
- QRS morphology depends on the site of the block:
Clinical Implications and Anatomical Correlations
- The width of the QRS complex provides important clues about the anatomical location of the block 1:
- Narrow QRS suggests AV nodal block (higher in conduction system)
- Wide QRS suggests infra-nodal block (lower in conduction system)
- In third-degree AV block with wide QRS, the site of block is usually below the His bundle 1
- The width of native QRS complexes can predict paced QRS duration in patients requiring pacemakers for AV block 2
Important Clinical Considerations
- Type II second-degree block, especially with wide QRS, has higher risk of progressing to complete heart block 1, 3
- Permanent pacing is generally recommended for:
- The prognosis of AV block depends on the site of block:
Diagnostic Pearls
- In cases with wide QRS and first or second-degree AV block, electrophysiological study may be required to determine the exact level of block 1
- 2:1 AV block cannot be classified as type I or II based on ECG alone since there's only one PR interval to examine before the blocked P wave 4
- Wide QRS in AV block may indicate more extensive conduction system disease and potentially worse outcomes with right ventricular pacing 2