Is Buscopan (Hyoscine butylbromide) safe during breastfeeding?

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Last updated: March 24, 2025View editorial policy

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From the Research

Buscopan (hyoscine butylbromide) is generally considered safe during breastfeeding, as it passes into breast milk in very small amounts, resulting in minimal exposure to the nursing infant. The medication works locally in the digestive tract to relieve spasms and cramping, with limited absorption into the bloodstream, further reducing potential transfer to breast milk 1.

Key Considerations

  • The typical adult dose is 10-20 mg taken up to four times daily.
  • If breastfeeding and needing to take Buscopan for digestive cramps or IBS symptoms, it is recommended to continue nursing the baby as usual.
  • However, it's always best to use the lowest effective dose for the shortest time needed.
  • Some mothers may notice a slight reduction in milk production as anticholinergic medications can theoretically affect milk supply, though this is uncommon with Buscopan.
  • If unusual symptoms in the baby such as irritability, drowsiness, or feeding difficulties are noticed after taking this medication, it is advised to contact the healthcare provider.

Evidence Summary

The safety of Buscopan during breastfeeding is supported by general principles of drug transfer into breast milk, as most drugs cause relatively low-level exposure below 10% of the weight-adjusted maternal dose 2. Although specific data on Buscopan is not provided in the referenced studies, the medication's pharmacokinetic properties suggest minimal risk to the breastfeeding infant. It is essential for healthcare providers to assess the risks and benefits for both mother and child when considering medication use during breastfeeding, as emphasized in several studies 3, 4, 5.

Clinical Implications

Given the available evidence, the use of Buscopan during breastfeeding is considered safe, with minimal risk of adverse effects on the infant. However, as with any medication, it is crucial to monitor the infant for any signs of unusual symptoms and to use the lowest effective dose for the shortest duration necessary. Healthcare providers should consult reliable resources, such as reference books or online medical literature, to stay updated on the safety of medications during breastfeeding 1, 2.

References

Research

Drugs in breastfeeding.

Australian prescriber, 2015

Research

Medication and breastfeeding.

Journal of biological regulators and homeostatic agents, 2012

Research

Drugs and breastfeeding: instructions for use.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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