Is smoking cigarettes more harmful than vaping?

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Last updated: October 13, 2025View editorial policy

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Smoking Cigarettes vs. Vaping: Health Impact Comparison

Smoking cigarettes is significantly more harmful than vaping, though vaping is not harmless and carries its own health risks. 1

Comparative Health Risks

Cigarette Smoking Risks

  • Smoking combustible cigarettes negatively impacts nearly every organ of the body and reduces life expectancy by approximately 10 years compared to non-smokers 1
  • Smoking is the leading cause of preventable mortality and morbidity worldwide 1
  • Globally, smoking and exposure to secondhand smoke are responsible for roughly 1 in 5 (21%) of all deaths attributed to coronary heart disease 1
  • Smoking increases the risk of all types of cardiovascular disease including coronary heart disease, ischemic stroke, and peripheral arterial disease 1
  • The relative risk of myocardial infarction in smokers under 50 years is five-fold higher than in non-smokers 1

Vaping Risks

  • E-cigarettes contain and emit numerous potentially toxic substances beyond just nicotine, though exposure is highly variable based on product characteristics and usage patterns 1
  • Compared with combustible tobacco cigarettes, e-cigarette use likely poses less risk, but is not harmless 1
  • Growing evidence shows e-cigarettes and their constituents (nicotine, vaporizing solvents, particulate matter, metals, and flavorings) can have deleterious effects on the cardiovascular system, respiratory system, and brain 1
  • Vaping has been associated with cases of exogenous lipoid pneumonia, diffuse alveolar hemorrhage, and vaping-associated bronchiolitis obliterans 2

Special Considerations

Youth Risk

  • E-cigarette use among youth poses a clear threat to public health with dramatic increases in usage among young people in the United States 1
  • E-cigarette use is associated with increased odds of smoking combustible cigarettes among adolescents who had no previous intention of smoking conventional cigarettes 1
  • The introduction of high-nicotine delivery systems has transformed the e-cigarette landscape and increased addiction potential for young people 1

Dual Use Concerns

  • Many e-cigarette users also continue to smoke cigarettes, and dual use is not associated with higher rates of quitting 1
  • Recent research suggests that dual use of vaping and smoking may be associated with higher risk of lung cancer than smoking alone 3
  • The Forum of International Respiratory Societies recommends that individuals using e-cigarettes to quit smoking should avoid using both combustible and electronic cigarettes simultaneously 4

Smoking Cessation Considerations

Efficacy of E-cigarettes for Cessation

  • Evidence is limited regarding the efficacy of e-cigarettes as a smoking cessation aid 1
  • A 2020 Cochrane review found only moderate evidence that quit rates were higher among those using nicotine e-cigarettes compared with nicotine replacement therapy or non-nicotine e-cigarettes 1
  • E-cigarettes are not approved as smoking cessation aids by regulatory agencies, unlike standard nicotine replacement therapies 5

Recommended Cessation Approaches

  • Pharmacotherapy plus counselling improves smoking cessation compared with either pharmacotherapy or counselling alone 1
  • Stopping smoking increases life expectancy at any age - those who quit at 30,40, or 50 years gain about 10,9, and 6 years of life expectancy, respectively, compared with continued smokers 1
  • The US Preventive Services Task Force recommends focusing on proven behavioral counseling and FDA-approved pharmacotherapy for smoking cessation rather than e-cigarettes 5

Clinical Recommendations

  • Healthcare providers should advise individuals to avoid both smoking and vaping for optimal health outcomes 4, 5
  • If patients are using e-cigarettes to quit smoking, they should be advised to avoid dual use and develop a plan to eventually quit e-cigarettes as well 4
  • Screening for tobacco, nicotine, and electronic cigarette use should be incorporated into routine healthcare visits 4
  • The benefits of smoking cessation on cardiovascular risk become apparent within 2-5 years after quitting 4

Pitfalls and Caveats

  • Many people incorrectly perceive e-cigarettes as harmless or significantly less harmful than traditional cigarettes 4
  • Long-term epidemiological studies of e-cigarettes are challenging because these products have evolved rapidly since their emergence 1
  • The claim that vaping is completely safe is not supported by current evidence, though it appears to be less harmful than combustible cigarettes 1, 6
  • Recent studies have raised concerns about potential long-term risks of vaping, including cardiovascular disease, chronic obstructive lung disease, and cancer 7

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Electronic cigarettes, vaping-related lung injury and lung cancer: where do we stand?

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2021

Research

Vaping, Smoking and Lung Cancer Risk.

Journal of oncology research and therapy, 2024

Guideline

Vaping's Impact on Cholesterol Levels and Cardiovascular Health

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Health Risks and Recommendations for Vaping After Quitting Smoking

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Harms of Electronic Cigarettes: What the Healthcare Provider Needs to Know.

Annals of the American Thoracic Society, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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