What are the guidelines for performing an arthrocentesis as indicated by CPT (Current Procedural Terminology) code 20600?

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Guidelines for Arthrocentesis Using CPT Code 20600

CPT code 20600 refers to arthrocentesis (joint aspiration) or injection of a small joint or bursa such as fingers, toes, or temporomandibular joint, which requires specific procedural techniques and sterile precautions to ensure patient safety and diagnostic accuracy. 1

Procedural Requirements

  • Transducers used for ultrasound-guided arthrocentesis should be covered with single-use sterile probe covers during the procedure 1
  • Single-use sterile gel packets should be used when performing arthrocentesis to prevent infection 1
  • Low-level disinfection of ultrasound probes is required between procedures 1

Diagnostic Indications

  • Arthrocentesis is indicated when septic arthritis is suspected, receiving a highest appropriateness rating (9/9) from the American College of Radiology 1
  • Joint fluid analysis should include total cell count, differential leukocyte count, and culture for aerobic and anaerobic organisms 1
  • Crystal analysis should be performed when clinically indicated to diagnose conditions like gout or pseudogout 1, 2

Imaging Guidance Considerations

  • Ultrasound guidance can improve accuracy of arthrocentesis, particularly for deeper or difficult-to-access joints 3
  • MRI with or without contrast may be complementary to arthrocentesis for evaluation of suspected septic arthritis 1
  • Plain radiographs should be obtained prior to arthrocentesis when evaluating for osteomyelitis, septic arthritis, or soft tissue infection 1

Anticoagulation Considerations

  • Arthrocentesis can be safely performed in patients receiving therapeutic anticoagulation without the need to reduce anticoagulation levels 4
  • A study of 640 arthrocentesis procedures found only 0.2% resulted in significant clinical bleeding in fully anticoagulated patients 4

Post-Procedural Management

  • For suspected prosthetic joint infections, withholding antimicrobial therapy for at least 2 weeks prior to arthrocentesis increases the likelihood of recovering an organism 1
  • Blood cultures should be obtained if fever is present, symptoms have acute onset, or if bloodstream infection is suspected 1, 2

Therapeutic Applications

  • Arthrocentesis alone has been shown to be as effective as arthrocentesis with hyaluronic acid or corticosteroid for pain reduction in temporomandibular joint disorders 5
  • Pain reduction of 30-40% can be expected following arthrocentesis procedures 5

Common Pitfalls to Avoid

  • Failing to distinguish between tendon calcification and bursal calcification, which may require different treatment approaches 6
  • Overlooking small calcifications that may be missed on plain radiographs but visible on ultrasound 6
  • Confusing calcific bursitis with joint effusion or synovitis, which can have similar clinical presentations 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Approach for Severe Joint Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Ultrasound-guided hip arthrocentesis in the ED.

The American journal of emergency medicine, 2007

Research

Is Hyaluronic Acid or Corticosteroid Superior to Lactated Ringer Solution in the Short-Term Reduction of Temporomandibular Joint Pain After Arthrocentesis? Part 1.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2017

Guideline

Diagnosis of Bursa Calcification

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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