Can Mirena (levonorgestrel) cause alopecia?

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From the Research

Yes, Mirena (levonorgestrel-releasing intrauterine system) can potentially cause hair loss in some women, as indicated by the most recent and highest quality study available 1. This is considered an uncommon side effect that may occur due to the hormonal effects of levonorgestrel, the synthetic progestin released by the device.

Key Points to Consider

  • Hair loss related to Mirena typically manifests as thinning hair rather than patchy baldness and is usually temporary.
  • The mechanism behind this side effect involves the progestin component potentially affecting hormone balance, particularly by influencing androgen levels which play a role in hair growth cycles, as discussed in earlier studies 2, 3, 4, 5.
  • If you experience significant hair loss after Mirena insertion, consult your healthcare provider to discuss your symptoms.

Recommendations for Management

  • They may recommend monitoring the situation, as hair growth often normalizes as your body adjusts to the hormonal changes.
  • Alternatively, they might suggest alternative contraceptive options if the hair loss is bothersome.
  • Maintaining good nutrition, reducing stress, and using gentle hair care products may help minimize hair loss while your body adapts to the hormonal changes.

Importance of Recent Evidence

  • The most recent study 1 highlights the importance of considering drug-induced hair loss, including that caused by hormonal contraceptives like Mirena, and emphasizes the reversibility of this condition upon discontinuation of the offending drug.

References

Research

Drug-induced hair loss.

Prescrire international, 2016

Research

Hair loss in women.

Seminars in cutaneous medicine and surgery, 2009

Research

Alopecia in women.

American family physician, 2003

Research

Drug reactions affecting hair: diagnosis.

Dermatologic clinics, 2007

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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