What is the treatment for a second-degree burn?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 15, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Treatment of Second-Degree Burns

The immediate treatment for second-degree burns involves cooling the burn with clean running water for 5-20 minutes, followed by application of appropriate dressings and referral to specialized care for burns involving critical areas or covering >10% body surface area in adults or >5% in children. 1

Immediate First Aid Steps

  • Cool the burn immediately with clean running water for 5-20 minutes to limit burn depth progression and reduce pain 1
  • Monitor children closely for signs of hypothermia during cooling 1, 2
  • Remove all jewelry before swelling occurs to prevent constriction and vascular ischemia 1
  • Administer over-the-counter pain medications such as acetaminophen or NSAIDs for pain management 1

Wound Cleaning and Assessment

  • Clean the wound with tap water, isotonic saline, or an antiseptic solution in a clean environment with appropriate pain control 1
  • Assess the burn for size, depth, and location to determine appropriate management 1
  • Second-degree burns are partial-thickness burns that may be superficial (involving epidermis and superficial dermis) or deep (extending into deeper dermis) 2, 3

Dressing Application

  • For small partial-thickness burns managed at home, apply petrolatum, petrolatum-based antibiotic ointment, honey, or aloe vera 1
  • Cover with a clean non-adherent dressing to protect the wound 1
  • Silver sulfadiazine cream 1% is indicated as an adjunct for prevention and treatment of wound sepsis in second and third-degree burns 4
  • Triple-antibiotic ointment has been shown to enhance reepithelialization and reduce scar depth compared to silver-based foam dressings in research studies 5

Special Considerations for Hand Burns

  • Hand burns require specialized care due to high risk of functional disability 2
  • For partial-thickness hand burns, loosely cover with a clean, non-adherent dressing and refer to a burn specialist or burn center immediately 2
  • Monitor for signs of compartment syndrome in circumferential burns 2

When to Seek Medical Attention

  • Burns involving the face, hands, feet, or genitals require immediate medical attention 1, 2
  • All full-thickness burns require medical attention 1
  • Burns covering >10% body surface area in adults or >5% in children require medical evaluation 1
  • Signs of inhalation injury (soot around nose/mouth, difficulty breathing, singed nasal hairs) require immediate medical attention 1

Pitfalls to Avoid

  • Do not use ice directly on burns as it may cause further tissue damage 2
  • Do not apply butter or oil to burns 2
  • Do not use external cooling devices (e.g., Water-Jel dressings) for prolonged periods due to risk of hypothermia 1
  • Avoid routine antibiotic prophylaxis for burn patients unless infection is present 1
  • Do not delay referral for partial or full-thickness burns in critical areas as this can lead to permanent functional impairment 2

Dressing Changes and Follow-up

  • Ideally, dressings should be re-evaluated daily to monitor healing progress 1
  • When applying dressings on limbs, prevent bandages from creating a tourniquet effect 1
  • Monitor distal perfusion in case of circular dressings 1
  • The most recent consensus (2024) emphasizes the importance of standardized approaches to second-degree burn management to improve outcomes 3, 6

References

Guideline

Initial Treatment for Second-Degree Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Hand Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Topical antibiotic ointment versus silver-containing foam dressing for second-degree burns in swine.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.