What is the treatment for a stomach virus?

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Last updated: October 15, 2025View editorial policy

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Treatment for Stomach Virus

The primary treatment for viral gastroenteritis is oral rehydration therapy (ORT) to prevent and treat dehydration, as the illness is typically self-limited and resolves within a few days without specific antiviral treatment.1

General Management Principles

  • Viral gastroenteritis is a self-limited illness typically lasting a few days, with virus replication restricted to the gut mucosa. The main risk is dehydration and electrolyte imbalance.1
  • The cornerstone of treatment is maintaining adequate hydration through oral rehydration therapy (ORT).1, 2
  • Most patients can be managed at home with appropriate fluid replacement.1

Rehydration Strategies

Oral Rehydration Therapy (ORT)

  • ORT is the first-line treatment for both children and adults with mild to moderate dehydration.1, 2
  • Commercial oral rehydration solutions containing appropriate glucose and electrolyte concentrations are effective.2, 3
  • For adults, maintenance of good hydration is particularly important, especially among elderly patients and those on diuretic medications.1
  • In a comparative study, solutions like Pedialyte, Gatorade, and other oral rehydration solutions were found to be effective in treating dehydration in adults with viral gastroenteritis.2

Intravenous Fluids

  • Hospitalization and intravenous fluid therapy are only required for cases with severe dehydration or when the patient/caretaker cannot provide adequate oral rehydration.1
  • Children with severe dehydration may require serum electrolyte, creatinine, and glucose measurements.3

Symptomatic Management

Anti-emetics

  • For persistent vomiting that interferes with oral rehydration, ondansetron may be considered.4, 3
  • Judicious use of ondansetron can increase the success of ORT and minimize the need for intravenous therapy and hospitalization.4, 3
  • In one study, bismuth subsalicylate reduced the duration of Norwalk virus infection from 27 to 20 hours in adults.1

Nutritional Management

  • Continue feeding during the illness - "feed through" approach.1
  • Breast milk has a protective effect against enteric infections and should be continued in infants.1
  • A mild, easily digestible diet can be offered as tolerated.2
  • Temporary lactose intolerance may occur following rotavirus infection (typically lasting 10-14 days), but most infants completely recover.1

Special Considerations

Children

  • Children have a higher risk of dehydration and respond well to ORT.1
  • Lack of access to medical care, rather than disease virulence, is a principal risk factor for death from gastroenteritis.1

Elderly and Immunocompromised Patients

  • Elderly patients require careful monitoring for dehydration.1
  • Immunocompromised patients may experience more severe or prolonged illness and may require specialized care.1

Prevention Measures

  • Vigorous handwashing with soap is necessary to control the spread of enteric pathogens.1
  • Thorough cleaning of environmental surfaces contaminated with feces or vomitus is required.1
  • Persons with symptoms should avoid preparing food for others and should be excluded from contact with susceptible individuals for at least 2 days after resolution of symptoms.1
  • Soiled linens should be handled minimally and washed with detergent in hot water.1

When to Seek Medical Attention

  • Signs of severe dehydration: decreased urination, dry mouth, sunken eyes, excessive thirst, lethargy, or altered mental status.1
  • Persistent vomiting preventing oral rehydration.4, 3
  • Bloody diarrhea or severe abdominal pain.1
  • High fever.1
  • Symptoms lasting more than 3-4 days without improvement.1

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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