What are the basics of electrocardiogram (ECG) interpretation?

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Last updated: October 16, 2025View editorial policy

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Basics of ECG Interpretation

A systematic approach to ECG interpretation is essential for accurate diagnosis of cardiac conditions, requiring careful analysis of rate, rhythm, axis, intervals, and waveform morphology. 1

Step-by-Step Approach to ECG Interpretation

1. Assess Heart Rate and Rhythm

  • Calculate heart rate by counting the number of large squares between consecutive R waves or by counting QRS complexes in a 6-second strip and multiplying by 10 (normal: 60-100 beats per minute) 1, 2
  • Evaluate rhythm regularity by examining R-R intervals for consistency to determine if the rhythm is regular or irregular 1
  • Identify the underlying rhythm (sinus, atrial, junctional, ventricular) based on P wave morphology and relationship to QRS complexes 1

2. Analyze Intervals and Segments

  • Measure PR interval (normal: 120-200 ms or 3-5 small squares) to assess AV conduction 1, 2
  • Measure QRS duration (normal: <120 ms or <3 small squares) to evaluate ventricular conduction 1, 3
  • Calculate QT interval and correct for heart rate (QTc, normal: <450 ms for men, <460 ms for women) to assess repolarization 1, 2
  • Examine ST segments for elevation or depression that may indicate ischemia, injury, or other pathology 1

3. Determine Electrical Axis

  • Examine leads I and aVF to quickly determine the quadrant of the axis (normal axis: between -30° and +90°) 1
  • Left axis deviation is characterized by a positive deflection in lead I and a negative deflection in aVF 1
  • Right axis deviation is characterized by a negative deflection in lead I and a positive deflection in aVF 1

4. Analyze P Waves, QRS Complexes, and T Waves

  • Evaluate P wave morphology (normal: upright in I, II, aVF; biphasic in V1) and measurements (normal: <120 ms duration, <2.5 mm amplitude) 1
  • Analyze QRS complex morphology for pathologic Q waves (>1 mm wide and >1/3 the height of the R wave) suggesting myocardial infarction 1
  • Assess R wave progression across precordial leads (normally R wave amplitude increases from V1 to V4 and then decreases toward V6) 1
  • Evaluate T wave morphology (normally upright in leads I, II, V3-V6, inverted in aVR, and variable in III, aVL, aVF, V1, and V2) 1

5. Look for Additional Features

  • Identify U waves, which may indicate hypokalemia, bradycardia, or other conditions 1
  • Assess for signs of chamber enlargement using P wave abnormalities and QRS voltage criteria 1
  • Identify conduction abnormalities such as PR prolongation and QRS widening 1

Technical Considerations

  • The fundamental frequency for the QRS complex at the body surface is 10 Hz, and most diagnostic information is contained below 100 Hz in adults 3
  • Inadequate high-frequency response results in systematic underestimation of signal amplitude and smoothing of notches and Q waves 3
  • Inadequate low-frequency response can result in important distortions of repolarization 3
  • Avoid improper electrode placement, especially chest leads, which can significantly alter ECG interpretation and lead to false diagnoses 2
  • Computerized ECG interpretations should always be verified by a qualified physician 1, 2

Special Considerations

  • Age and gender affect normal ECG parameters (e.g., QT intervals are typically longer in women) 1
  • Certain medications can affect ECG findings (e.g., antiarrhythmics, psychotropics) 1
  • Always interpret ECG findings in the context of the patient's clinical presentation 2
  • The QRS of infants often contains important components as high as 250 Hz, requiring different filtering parameters 3

Common Pitfalls to Avoid

  • Over-reliance on computerized interpretation without physician verification 2
  • Interpreting ECG findings in isolation without considering clinical context 2
  • Inadequate filtering that can distort important waveform components 3
  • Failure to recognize that interpretation varies even among expert electrocardiographers, emphasizing the need for ongoing education 2

References

Guideline

ECG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

ЭКГ Интерпретация и Рентгенографические Изображения

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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