Guidelines for Electrocardiogram (ECG) and Management of Results
ECGs should be performed in all patients with known cardiovascular disease, suspected cardiac disease, or those at high risk of developing cardiovascular disease, with management guided by specific findings and clinical context. 1
Indications for ECG Testing
Class I Indications (Strongly Recommended)
Patients with known cardiovascular disease
Patients with suspected cardiac disease
Medication monitoring
Device monitoring
Procedural indications
Class II Indications (May Be Reasonable)
- Adults >40 years old without symptoms but with risk factors 1
- Patients with hemodynamically insignificant heart disease 1
- Patients with mild hypertension 1
Class III Indications (Not Recommended)
- Asymptomatic young adults (<30 years) with no risk factors 1
- Routine follow-up in asymptomatic patients with recent normal ECG 1
- Patients receiving therapy not known to produce ECG changes 1
Management of ECG Results
Normal ECG
- In patients with chest pain, a normal ECG does not rule out acute coronary syndrome (1-4% of patients with normal ECGs may still have AMI) 3
- Clinical assessment remains crucial - history is the most important tool in chest pain evaluation 3
- Patients with normal ECGs and low clinical suspicion may be considered for outpatient evaluation 4
Abnormal ECG Without Clear Ischemia
- Patients with bundle branch blocks or other non-ischemic abnormalities have a relatively low risk (3.6%) but not zero risk of AMI 4
- Management should be based on cardiac risk profile (age, gender, hypertension, diabetes, smoking history) 4
Abnormal ECG With Possible Ischemia
- Patients with nonspecific ST and T wave changes have an intermediate risk (14.6%) of AMI 4
- These patients generally warrant admission and further cardiac evaluation 4
Abnormal ECG With Definite Ischemia
- Patients with ST-segment elevation or depression have a high risk (54.2%) of AMI 4
- These patients require immediate hospital admission and consideration for emergent reperfusion therapy 5
Follow-up ECG Recommendations
Frequency of follow-up ECGs should be determined by the responsible physician based on:
- Known natural history of the disease
- Patient's age
- Effectiveness of therapy
- Severity of disease at last evaluation 1
New or changing symptoms that warrant repeat ECG include:
- Syncope or near-syncope
- Changes in angina pattern
- New or worsening dyspnea
- Unexplained fatigue or weakness
- Palpitations 1
Important Considerations
- ECG interpretation requires qualified physician review - computer interpretation alone is insufficient 1
- Overreliance on a normal ECG in a patient with classic anginal symptoms is dangerous 3
- Serial ECGs may be necessary in evolving conditions or when symptoms change 1
- Compare with previous ECGs when available to identify significant changes 5
Pitfalls to Avoid
- Do not rule out AMI based solely on a normal ECG - history and clinical assessment remain crucial 3
- Do not delay treatment for obvious ST-elevation MI while waiting for cardiac marker results 5
- Do not rely solely on computer interpretation - physician review is essential 1
- Do not forget that many non-cardiac conditions can cause ECG abnormalities (electrolyte disturbances, drug effects, etc.) 1
- Do not assume all ST changes represent ischemia - left ventricular hypertrophy, cardiomyopathies, and other conditions can cause similar changes 5