Differential Diagnosis for Multiple Inguinal Lymphadenopathies with Skin Lesions and Warm Sensation
Single Most Likely Diagnosis
- Lymphogranuloma Venereum (LGV): This is a sexually transmitted infection caused by Chlamydia trachomatis, which can lead to inguinal lymphadenopathy, often accompanied by skin lesions and systemic symptoms such as fever, which might cause a warm sensation.
Other Likely Diagnoses
- Cat Scratch Disease: Caused by Bartonella henselae, transmitted through cat scratches or bites, leading to lymphadenopathy, which can be accompanied by a papule or pustule at the site of the scratch.
- Tuberculosis: Can cause lymphadenopathy and skin lesions, especially in immunocompromised individuals or those from endemic areas. The skin lesions can be accompanied by systemic symptoms like fever, causing a warm sensation.
- Syphilis: A sexually transmitted infection that can cause lymphadenopathy and skin lesions (chancre in primary syphilis), which might be accompanied by a warm sensation due to inflammation.
Do Not Miss Diagnoses
- Malignant Lymphoma: Although less common, lymphadenopathy can be a presenting feature of lymphoma. Skin lesions and systemic symptoms like fever (causing a warm sensation) can also occur, making it crucial not to miss this diagnosis due to its severe implications.
- HIV Infection: Can present with lymphadenopathy and skin lesions (due to opportunistic infections or as part of the acute retroviral syndrome), along with systemic symptoms like fever, which might cause a warm sensation.
Rare Diagnoses
- Kikuchi-Fujimoto Disease: A rare, self-limiting condition that causes lymphadenopathy, often accompanied by fever and night sweats, which could contribute to a warm sensation. Skin lesions are less common but can occur.
- Whipple's Disease: A rare, systemic bacterial infection that can cause lymphadenopathy, skin lesions, and systemic symptoms including fever, which might cause a warm sensation. It's more common in immunocompromised individuals.