What are the causes of tibialis anterior (TA) muscle weakness with sparing of the tibialis posterior (TP) muscle?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Tibialis anterior weakness sparing tibialis posterior is most commonly caused by a common peroneal nerve injury or compression at the fibular head, which affects the deep peroneal nerve supplying the tibialis anterior while sparing the tibialis posterior, as supported by the study published in 2023 1.

Causes of Tibialis Anterior Weakness

The causes of tibialis anterior weakness with sparing of the tibialis posterior muscle can be attributed to several conditions, including:

  • Common peroneal nerve injury or compression at the fibular head, affecting the deep peroneal nerve supplying the tibialis anterior
  • L4 radiculopathy affecting primarily the anterior compartment
  • Anterior compartment syndrome where increased pressure damages the tibialis anterior muscle
  • Direct trauma to the tibialis anterior muscle
  • Certain myopathies that preferentially affect the anterior compartment muscles
  • Diabetic neuropathy with asymmetric involvement affecting the peroneal nerve more than the tibial nerve
  • Multiple sclerosis and other demyelinating disorders causing isolated weakness patterns due to selective central nervous system lesions

Diagnosis and Treatment

Diagnosis typically involves physical examination, nerve conduction studies, electromyography, and sometimes imaging studies like MRI to identify the underlying cause. Treatment depends on the specific etiology but may include addressing nerve compression, physical therapy, ankle-foot orthoses for foot drop, and in some cases, surgical intervention, as discussed in the study published in 2024 2. Some key points to consider in the diagnosis and treatment of tibialis anterior weakness include:

  • The importance of manual muscle testing in assessing tibialis anterior muscle weakness, as highlighted in the study published in 2023 1
  • The use of electrophysiological assessments, such as compound muscle action potentials, in evaluating the function of the lumbar and sacral peripheral motor nerves, as discussed in the study published in 2024 2
  • The potential benefits of surgical intervention, such as tendon transfer, in treating tibialis anterior weakness, as reported in the case study published in 2022 3

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.