What is the treatment for costochondritis?

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Last updated: October 16, 2025View editorial policy

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Treatment for Costochondritis

The first-line treatment for costochondritis is NSAIDs at the maximum tolerated and approved dosage, with evaluation of treatment response after 2-4 weeks. 1

Pharmacological Management

  • NSAIDs should be used at the lowest effective dose for the shortest possible period, considering the patient's risk factors for gastrointestinal, liver, and cardiorenal toxicity 1
  • Acetaminophen (paracetamol) can be used as an alternative or adjunct for pain relief, especially when NSAIDs are contraindicated 1
  • Topical NSAIDs should be considered before oral NSAIDs to minimize systemic side effects 1
  • Short courses of oral prednisolone or intra-articular glucocorticoid injections may be considered as bridging options while awaiting the effect of other agents 1
  • Long-term use of glucocorticoids should be avoided due to potential adverse effects 1

Non-Pharmacological Interventions

  • Local heat or cold applications to the affected area can provide symptomatic relief 1, 2
  • Patient education about the condition and its typically self-limiting nature is essential 1, 3
  • Stretching exercises have shown significant improvement in pain reduction compared to control groups 4
  • Manual therapy techniques including rib manipulation and soft tissue mobilization have demonstrated complete resolution of symptoms in cases of atypical costochondritis 5
  • Physical therapy utilizing an impairment-based approach that includes manual therapy and therapeutic exercise may facilitate resolution of costochondritis 6
  • Patients should avoid activities that produce chest muscle overuse 3

Treatment Algorithm

  1. Initial Management:

    • Start with NSAIDs at maximum tolerated dose 1
    • Apply local heat or cold applications 2, 1
    • Advise rest from aggravating activities 3
  2. If inadequate response after 2-4 weeks:

    • Consider adding acetaminophen 1
    • Refer for physical therapy with focus on stretching exercises and manual therapy 6, 4
    • Consider short-course glucocorticoids as a bridging treatment 1
  3. For persistent cases (atypical costochondritis):

    • Implement multimodal physical therapy including manipulative therapy, instrument-assisted soft tissue mobilization, and stretching 5, 6

Important Considerations

  • Costochondritis is usually self-limited and benign, but it's essential to rule out more serious causes of chest pain, particularly in patients over 35 or those with cardiac risk factors 3
  • Monitor for adverse effects with prolonged NSAID use, particularly in elderly patients and those with comorbidities 1
  • Infectious costochondritis, though rare, requires different management including antibiotics and possibly surgical debridement 7
  • While costochondritis typically resolves in weeks to months, some cases can become persistent (atypical costochondritis), requiring more intensive physical therapy interventions 5, 6

References

Guideline

Costochondritis Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Costochondritis: diagnosis and treatment.

American family physician, 2009

Research

Stretching exercises for costochondritis pain.

Giornale italiano di medicina del lavoro ed ergonomia, 2009

Research

IMPAIRMENT BASED EXAMINATION AND TREATMENT OF COSTOCHONDRITIS: A CASE SERIES.

International journal of sports physical therapy, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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