What is the procedure for cystoscopy (cystoscopic examination) in females?

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Last updated: October 17, 2025View editorial policy

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Cystoscopy Procedure in Females

Cystoscopy in females involves direct visualization of the bladder and urethra using a flexible or rigid cystoscope, with flexible cystoscopy being preferred due to less pain, fewer post-procedure symptoms, simplified patient positioning, and reduced procedure time. 1

Patient Preparation and Positioning

  • Female patients are typically positioned in a frog-leg supine position for optimal access to the urethra 2
  • The procedure requires sterile preparation including:
    • Flexible or rigid cystoscope (flexible preferred)
    • Irrigant solution
    • Lubricating gel
    • Sterile gloves
    • Sterile drapes 2

Procedural Steps for Female Cystoscopy

  1. External Preparation:

    • Cleanse the external genitalia with antiseptic solution
    • Apply liberal amounts of lubricating gel to the cystoscope 2, 3
  2. Urethral Access:

    • The female urethra is shorter (approximately 3-4 cm) compared to males, making insertion technically easier 1
    • Gentle separation of the labia for clear visualization of the urethral meatus 2
    • The cystoscope is inserted directly into the urethral meatus 2
  3. Bladder Examination:

    • Complete visualization of the bladder mucosa, urethra, and ureteral orifices 1
    • Systematic inspection of the entire bladder including:
      • Trigone area (triangular region between ureteral orifices and bladder neck)
      • Lateral walls
      • Posterior wall
      • Dome of the bladder
      • Bladder neck area 2, 4
    • Assessment of ureteral orifices for patency and position 4
  4. Irrigation:

    • Continuous irrigation is used to distend the bladder for optimal visualization 2
    • The irrigation fluid allows for clear visualization of the bladder mucosa 3

Equipment Considerations

  • Flexible Cystoscopy: Currently considered the standard tool due to:

    • Significantly decreased pain and discomfort
    • Better visualization of certain areas (e.g., anterior bladder neck)
    • Improved patient tolerance 1, 3
  • Rigid Cystoscopy: May still be used in certain circumstances but generally causes more discomfort 3

  • Newer Technologies: Wireless cystoscopes with 4K ultra HD imaging are emerging, offering portability and lower cost 5

Clinical Applications

  • Diagnostic evaluation for hematuria 1, 4
  • Surveillance for bladder cancer 3
  • Evaluation of lower urinary tract symptoms 1
  • Assessment of urinary dysfunction 1
  • Identification of bladder or urethral abnormalities such as:
    • Bladder tumors
    • Urethral diverticula
    • Interstitial cystitis
    • Foreign bodies 4

Post-Procedure Care

  • Patients may experience mild discomfort or burning with urination
  • Small amount of blood in urine may be normal immediately after the procedure
  • Increased fluid intake is recommended to help flush the bladder 2

Common Pitfalls and Considerations

  • Inadequate Visualization: Ensure proper irrigation and systematic examination of all bladder surfaces 2
  • Patient Discomfort: Use of flexible cystoscope and adequate lubrication can minimize discomfort 1, 3
  • Infection Risk: Maintain strict sterile technique to prevent urinary tract infections 2
  • Anatomical Variations: Be aware of potential anatomical variations such as duplicated ureteral orifices or ureteroceles 4

For patients with urinary dysfunction, fluoroscopy voiding cystourethrography may be considered as an appropriate initial imaging study when imaging is deemed necessary after clinical evaluation 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Procedural Module: Flexible Cystoscopy.

Journal of endourology, 2018

Research

Cystoscopic findings: a video tutorial.

International urogynecology journal, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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