What is the management for a non-adhering sutures site?

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Management of Non-Adhering Suture Sites

For non-adhering suture sites, continuous subcuticular sutures are recommended over interrupted sutures to reduce the risk of wound dehiscence, while considering antimicrobial-coated sutures to minimize infection risk. 1

Assessment of Non-Adhering Suture Sites

  • Evaluate for signs of wound dehiscence, which is more common with tissue adhesives than with sutures (RR 3.35; 95% CI 1.53 to 7.33) 1
  • Check for suture abscesses, which may occur with or without adhesive strips (documented in both scenarios in clinical studies) 1
  • Monitor for signs of infection such as increasing pain, redness, swelling, or discharge 2
  • Assess for spitting sutures, which can occur at sites without adhesive strips 1

Management Approach

Primary Interventions

  • Consider replacing non-adhering sutures with continuous subcuticular sutures, which show lower rates of superficial wound dehiscence compared to interrupted sutures (RR 0.08; 95% CI 0.02 to 0.35) 1
  • Use sutures rather than tissue adhesives when wound integrity is compromised, as sutures are significantly better for minimizing dehiscence 1
  • For contaminated wounds or those at high risk of infection, use triclosan-coated antimicrobial sutures, which significantly reduce surgical site infection risk (OR 0.72; 95% CI 0.59–0.88, P = 0.001) 1

Adjunctive Measures

  • Adding adhesive strips to non-adhering suture sites does not significantly improve outcomes or reduce scar width (mean scar width 1.1 [0.8] mm for both methods, P = .89) 1
  • Keep the wound clean and dry for 24-48 hours after reapplication of closure material 2
  • Consider fibrin sealants as an adjunct to sutures in complex wounds or areas where additional support is needed 3

Specific Suture Selection

  • For wounds requiring extended support, choose suture materials that retain 50-75% of their original tensile strength after 1 week (such as 4-0 poliglecaprone or 4-0 polyglactin) 1
  • For high-tension areas prone to dehiscence, avoid tissue adhesives as they have higher failure rates compared to sutures 4
  • In cases where infection is present or suspected, antimicrobial sutures (particularly triclosan-coated) should be used as they demonstrate consistent results in reducing infection risk 1

Special Considerations

  • Pain disproportionate to the severity of the wound may suggest deeper complications requiring more aggressive intervention 2
  • In patients with factors that may impair wound healing (diabetes, immunosuppression, etc.), sutures are preferable to tissue adhesives due to lower dehiscence rates 4
  • For cosmetically sensitive areas, note that there is no significant difference in cosmetic outcomes between sutures with or without adhesive strips (patient assessment scale scores of 14.0 [7.6] vs 14.7 [7.6], P = .39) 1

Pitfalls to Avoid

  • Avoid using tissue adhesives alone in high-tension areas as they have a higher risk of dehiscence compared to sutures 1
  • Do not assume that adding adhesive strips to sutures will improve outcomes, as evidence shows no significant benefit 1
  • Continuous tightly pulled sutures can strangulate wound edges, compromising healing 1
  • When replacing sutures, recognize that the number needed to treat to prevent one dehiscence when choosing sutures over tissue adhesives is 43 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Skin Glue for Wound Closure

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Suture support: is it advantageous?

American journal of surgery, 2001

Research

Tissue adhesives for closure of surgical incisions.

The Cochrane database of systematic reviews, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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