How do I interpret an electrocardiogram (ECG)?

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Last updated: October 19, 2025View editorial policy

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Systematic Approach to ECG Interpretation

To accurately interpret an electrocardiogram (ECG), follow a systematic approach that evaluates rate, rhythm, intervals, axis, and morphology while considering the clinical context, as this methodology significantly reduces diagnostic errors and improves patient outcomes. 1

Step-by-Step ECG Interpretation Algorithm

1. Assess Technical Quality

  • Evaluate the quality of the recording and identify any technical artifacts that may affect interpretation 1
  • Ensure proper lead placement, as misplaced electrodes can significantly alter ECG interpretation and lead to false diagnoses 1

2. Calculate Heart Rate

  • Count the number of QRS complexes in a 6-second strip and multiply by 10, or use the formula 300 divided by the number of large boxes between consecutive R waves 1
  • Normal sinus rhythm has a rate between 60-100 beats per minute in adults 1

3. Determine Rhythm

  • Identify the underlying rhythm by examining if there's a P wave before each QRS complex with consistent PR interval (sinus rhythm) 1
  • Note any irregularities such as premature beats, pauses, or completely irregular patterns that might suggest atrial fibrillation 1

4. Measure Intervals

  • PR interval: Normal 120-200 ms (3-5 small boxes) 1
  • QRS duration: Normal <120 ms (less than 3 small boxes) 1
  • QT interval: Calculate QTc using Bazett's formula, with normal values <450 ms for men and <460 ms for women 1

5. Determine Electrical Axis

  • Examine leads I and aVF: 1
    • Normal axis: +90° to -30° (positive in both leads I and aVF)
    • Left axis deviation: -30° to -90° (positive in lead I, negative in aVF)
    • Right axis deviation: +90° to +180° (negative in lead I, positive in aVF)
    • Extreme axis deviation: +180° to -90° (negative in both leads I and aVF)

6. Assess Chamber Enlargement

  • Look for voltage criteria for left ventricular hypertrophy: S in V1 + R in V5 or V6 >3.5 mV 1
  • Assess for atrial enlargement patterns 1

7. Evaluate for Ischemia, Injury, and Infarction

  • Examine ST-segment deviations: ST elevation (>0.1 mV in limb leads or >0.15-0.2 mV in precordial leads) may indicate acute injury 1
  • Look for T-wave abnormalities (inversion, hyperacute, flattening) 1
  • Identify pathological Q waves (>0.04 seconds or >25% of the R wave amplitude) suggesting myocardial infarction 1
  • Note the location of abnormalities to determine the affected coronary territory 1

Common Pitfalls to Avoid

  • Over-reliance on computer interpretation without physician verification, as errors in computer interpretation are still common 1, 2
  • Interpreting ECG findings in isolation without considering clinical context 1
  • Failure to compare with previous ECGs when available 1
  • Inadequate filtering settings, which can distort waveforms and affect measurements 1

Maintaining ECG Interpretation Competency

  • Continuing medical education through seminars or self-assessment programs is essential, especially for physicians who read ECGs infrequently 2
  • Consider periodic self-study to ensure skills remain current 2
  • Utilize available resources such as quality improvement programs with ECG overreading and feedback by expert electrocardiographers, self-paced interactive computer modules, and workshops 2

Clinical Context Importance

  • Always interpret the ECG in the context of the patient's clinical presentation, as the same ECG finding may have different implications depending on symptoms 1, 3
  • Noncardiologists are more affected by the context of the patient's clinical history and automated computer interpretation than cardiologists when interpreting an ECG 2
  • Cardiologists demonstrate greater accuracy than noncardiologists in ECG interpretation during standardized examinations when minimal history is given 2

By following this systematic approach to ECG interpretation, you can improve diagnostic accuracy and enhance patient care through proper identification of cardiac abnormalities.

References

Guideline

EKG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Basic surface electrocardiogram interpretation for the pharmacist.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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