How do I interpret an electrocardiogram (ECG)?

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Last updated: October 23, 2025View editorial policy

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Systematic Approach to ECG Interpretation

To properly interpret an electrocardiogram (ECG), you should follow a systematic approach that evaluates rate, rhythm, axis, intervals, and waveform morphology, as this methodical analysis is essential for accurate diagnosis of cardiac conditions. 1

Step-by-Step ECG Interpretation Process

1. Assess Heart Rate

  • Calculate heart rate by counting the number of large squares between consecutive R waves or by counting QRS complexes in a 6-second strip and multiplying by 10 1
  • Normal heart rate ranges from 60-100 beats per minute 1

2. Evaluate Rhythm

  • Examine R-R intervals for consistency to determine if the rhythm is regular or irregular 1
  • Identify the underlying rhythm (sinus, atrial, junctional, ventricular) based on P wave morphology and relationship to QRS complexes 1

3. Analyze Intervals and Segments

  • Measure PR interval (normal: 120-200 ms or 3-5 small squares) to assess AV conduction 1
  • Evaluate QRS duration (normal: <120 ms or <3 small squares) to assess ventricular conduction 1
  • Calculate QT interval and correct for heart rate (QTc, normal: <450 ms for men, <460 ms for women) 1

4. Determine Electrical Axis

  • Examine leads I and aVF to quickly determine the quadrant of the axis 1
  • Normal axis is between -30° and +90° 1
  • Left axis deviation: positive deflection in lead I and negative deflection in aVF 1
  • Right axis deviation: negative deflection in lead I and positive deflection in aVF 1

5. Analyze Waveform Morphology

  • P waves: Evaluate morphology (normal: upright in I, II, aVF; biphasic in V1), duration (<120 ms), and amplitude (<2.5 mm) 1
  • QRS complexes: Look for pathologic Q waves (>1 mm wide and >1/3 the height of the R wave) suggesting myocardial infarction 1
  • Assess R wave progression across precordial leads (normally increasing from V1 to V4, then decreasing toward V6) 1
  • ST segments: Check for elevation or depression measured at the J point, which may indicate ischemia or injury 1
  • T waves: Normally upright in leads I, II, V3-V6, inverted in aVR, and variable in III, aVL, aVF, V1, and V2 1

6. Look for Additional Features

  • U waves: May indicate hypokalemia, bradycardia, or other conditions 1
  • Signs of chamber enlargement: P wave abnormalities and QRS voltage criteria 1
  • Conduction abnormalities: PR prolongation and QRS widening 1

Common Pitfalls and Considerations

  • Computer interpretations should always be verified by a qualified physician as errors in computer interpretation are common 2, 1
  • Technical factors like electrode placement and filtering can affect ECG appearance and interpretation 1
  • Age and gender affect normal ECG parameters (e.g., QT intervals are typically longer in women) 1
  • Certain medications can affect ECG findings (e.g., antiarrhythmics, psychotropics) 1
  • When analyzing pacemaker ECGs, apply the same systematic approach used for any other ECG, checking for effectiveness of pacing and potential malfunctions 3

Training Requirements

  • Proficiency in ECG interpretation requires a combination of knowledge, skill, and practical clinical experience 2
  • The American College of Cardiology/American Heart Association recommends interpretation of 500 ECGs under supervision to attain initial competency 2
  • To maintain competency in ECG interpretation, reading approximately 100 ECGs yearly is advised 2

Remember that while major interpretation errors are common (4% to 33%), adverse patient outcomes resulting from these errors are relatively rare, typically occurring in less than 1% of interpretations 2.

References

Guideline

ECG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[Analysis of pacemaker ECGs].

Herzschrittmachertherapie & Elektrophysiologie, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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