Treatment Options for Conditions Requiring Pads
For heavy menstrual bleeding, the levonorgestrel-releasing intrauterine device (LNG-IUD) is the most effective medical therapy, reducing menstrual blood loss by 71-95%, while for urinary incontinence, first-line treatment includes lifestyle modifications, pelvic floor exercises, and bladder training. 1, 2, 3
Heavy Menstrual Bleeding Treatment Options
First-Line Treatments
- Combined oral contraceptives (COCs) with 30-35 μg of ethinyl estradiol are recommended as initial therapy for heavy menstrual bleeding, providing both menstrual regulation and contraception 4, 5
- The levonorgestrel-releasing intrauterine device (LNG-IUD) is highly effective for controlling heavy bleeding (comparable to endometrial ablation), with 71-95% reduction in menstrual blood loss 1, 2
- Tranexamic acid can reduce menstrual blood loss by 20-60%, though should be avoided in women with spontaneous coronary artery dissection (SCAD) due to thrombosis risk 1, 2
- NSAIDs can be used for 5-7 days to treat unscheduled spotting or heavy bleeding in users of various contraceptive methods 1
Second-Line Treatments
- Depot Medroxyprogesterone Acetate (DMPA) can be considered as a second-line treatment for heavy menstrual bleeding 4, 5
- Cyclic oral progestin treatment can reduce bleeding by approximately 87% and often results in irregular but lighter bleeding 1
- For women with persistent heavy bleeding despite medical therapy, endometrial ablation techniques (thermal balloon, microwave, radiofrequency) may be considered 1, 2
Special Considerations
- For patients with cardiovascular risk factors or contraindications to COCs, the LNG-IUD is recommended as first-line treatment 4
- For women on antiplatelet therapy experiencing heavy menstrual bleeding, reassessing the indication for ongoing antiplatelet therapy is an important first step 1
- Patients with hemodynamic instability or bleeding that saturates a large pad hourly for at least 4 hours warrant urgent evaluation 1
Urinary Incontinence Treatment Options
First-Line Treatments
- Lifestyle modifications including weight loss, adequate hydration, avoiding excessive fluids, and regular voiding intervals can reduce urgency incontinence episodes 6, 3
- Pelvic floor muscle exercises (Kegels) should be initiated as first-line treatment for all types of urinary incontinence 6, 3
- Bladder training programs help establish regular voiding patterns and can improve both stress and urgency incontinence 6, 3
Pharmacological Options
- For urgency urinary incontinence, anticholinergic medications like oxybutynin can be effective, though they should be used cautiously in elderly patients due to prolonged elimination half-life 7, 6
- β3-adrenergic agonists are an alternative medication class for urgency incontinence with potentially fewer side effects than anticholinergics 8, 6
- For postmenopausal women, local estrogen therapy can help improve urinary symptoms by strengthening urogenital tissues 3
Advanced Interventions
- For refractory urgency incontinence, specialist treatments include onabotulinumtoxinA injections, percutaneous nerve stimulation, or implanted neuromodulators 6, 3
- For stress incontinence not responding to conservative measures, surgical options like midurethral slings have high success rates (48-90% improvement) 6
Treatment Algorithm
- Identify the specific condition requiring pad use (heavy menstrual bleeding vs. urinary incontinence)
- For heavy menstrual bleeding:
- Start with LNG-IUD or COCs (if no contraindications)
- Add NSAIDs during heavy bleeding episodes
- Consider endometrial ablation if medical therapy fails
- For urinary incontinence:
- Begin with lifestyle modifications and pelvic floor exercises
- Add pharmacotherapy based on incontinence type (anticholinergics or β3-agonists for urgency)
- Consider surgical options for persistent stress incontinence
Important Caveats
- Always rule out underlying pathology before initiating treatment (infection, malignancy, structural abnormalities) 2, 6
- COCs increase the risk of venous thromboembolism three to fourfold (up to 4 per 10,000 woman-years) 4, 5
- Anticholinergic medications for urinary incontinence may alter absorption of concomitantly administered drugs and should be used cautiously in elderly patients 7
- Only 25% of women with urinary incontinence seek or receive treatment despite effective options being available 6